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髋关节置换术后维生素 E 及非维生素 E 补充型内衬杯的位置及其对聚乙烯磨损的影响:5 年随访的放射学结果。

Cup positioning and its effect on polyethylene wear of vitamin E- and non-vitamin E-supplemented liners in total hip arthroplasty: radiographic outcome at 5-year follow-up.

机构信息

Department of Orthopedics, Trauma, and Reconstructive Surgery, University Hospital Halle (Saale), Halle (Saale), Germany.

Department of Orthopedics, Trauma and Reconstructive Surgery, Marienhospital Mülheim an Der Ruhr, Chair of Orthopedics and Trauma Surgery, University of Duisburg-Essen, Essen, Germany.

出版信息

Arch Orthop Trauma Surg. 2023 Mar;143(3):1679-1688. doi: 10.1007/s00402-022-04424-2. Epub 2022 Apr 10.

Abstract

BACKGROUND

Aseptic loosening remains a challenging problem after total hip arthroplasty. Accurate cup placement and supplementation of antioxidants in acetabular liners might reduce material failure rates. The aim of this study is to assess the effect of the cup position on the wear behaviour of UHMWPE-XE and UHMWPE-X liners in vivo using virtual radiographs.

METHODS

We conducted a prospective, randomized, controlled, multicenter trial. Clinical data of 372 probands were analyzed. Anteroposterior pelvic X-rays of 324 patients immediately postoperatively and after 1 and 5 years were evaluated by the RayMatch® analysis software regarding cup position and wear behaviour.

RESULTS

Mean cup anteversion was 20.3° (± 7.4) and inclination was 41.9° (± 7.0) postoperatively. 62.3% of all patients had an anteversion and inclination within the Lewinnek safe zone. Anterior and anterolateral approaches led to significantly higher cup anteversion compared to lateral approaches (27.3° ± 5.5; 20.9° ± 7.2; 17.5° ± 6.6; p < 0.001 and p = 0.001, respectively). Mean anteversion increased to 24.6° (± 8.0) after 1 year (p < 0.001). Only one revision occurred because of implant dislocation. Wear rates from UHMWPE-X and UHMWPE-XE did not differ significantly. Anteversion angles ≥ 25° correlated to increased polyethylene wear (23.7 µm/year ± 12.8 vs. 31.1 µm/year ± 22.8, p = 0.012) and this was amplified when inclination angles were ≥ 50° (23.6 µm/year ± 12.8 vs. 38.0 µm/year ± 22.7, p = 0.062).

CONCLUSION

Anterior approaches lead to the highest inaccuracy of cup placement, but cup positioning outside the Lewinnek safe zone does not necessarily cause higher dislocation rates. Moreover, mean anteversion increased by approximately four degrees within the first year after operation, which is expected to be functional due to a regularization of pelvic tilt after intervention. Mid-term wear rates of UHMWPE-X and UHMWPE-XE liners are comparable, but steep cup positions lead to significantly increased polyethylene wear. In summary, a re-evaluation of target zones for intraoperative cup positioning might be considered. In the long-term reduced oxidative embrittlement could lead to superior wear behaviour of vitamin E-blended liners.

摘要

背景

全髋关节置换术后无菌性松动仍然是一个具有挑战性的问题。髋臼衬垫中准确的杯放置和抗氧化剂的补充可能会降低材料失效的概率。本研究的目的是使用虚拟射线照相术评估杯位置对 UHMWPE-XE 和 UHMWPE-X 衬垫在体内磨损行为的影响。

方法

我们进行了一项前瞻性、随机、对照、多中心试验。分析了 372 名患者的临床数据。术后即刻和 1 年、5 年后,324 名患者的骨盆前后位 X 射线通过 RayMatch®分析软件评估杯位置和磨损情况。

结果

术后平均杯前倾角为 20.3°(±7.4),倾斜角为 41.9°(±7.0)。62.3%的患者杯的前倾角和倾斜角均在 Lewinnek 安全区内。前侧和前外侧入路与外侧入路相比,杯前倾角明显更高(27.3°±5.5;20.9°±7.2;17.5°±6.6;p<0.001 和 p=0.001)。术后 1 年,平均前倾角增加至 24.6°(±8.0)(p<0.001)。仅因假体脱位发生 1 例翻修。UHMWPE-X 和 UHMWPE-XE 的磨损率无显著差异。前倾角≥25°与聚乙烯磨损增加相关(23.7 µm/年±12.8 与 31.1 µm/年±22.8,p=0.012),当倾斜角≥50°时,这种相关性更为明显(23.6 µm/年±12.8 与 38.0 µm/年±22.7,p=0.062)。

结论

前侧入路导致杯放置的不准确程度最高,但杯的位置超出 Lewinnek 安全区不一定会导致更高的脱位率。此外,术后第一年,平均前倾角增加了约 4 度,这是由于术后骨盆倾斜的正常化而预期的功能变化。UHMWPE-X 和 UHMWPE-XE 衬垫的中期磨损率相当,但陡峭的杯位会导致聚乙烯磨损显著增加。总的来说,可能需要重新评估术中杯定位的目标区域。从长远来看,减少氧化脆性可能会导致维生素 E 混合衬垫具有更好的磨损性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d6a/9957849/953b7d5dd91d/402_2022_4424_Fig1_HTML.jpg

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