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用于模拟COVID-19疫情动态的分数阶SEIQRDP模型

Fractional-Order SEIQRDP Model for Simulating the Dynamics of COVID-19 Epidemic.

作者信息

Bahloul Mohamed A, Chahid Abderrazak, Laleg-Kirati Taous-Meriem

机构信息

Computer, Electrical, and Mathematical Sciences, and Engineering Division (CEMSE)King Abdullah University of Science, and Technology (KAUST).

Computer, Electrical, and Mathematical Sciences, and Engineering Division (CEMSE)King Abdullah University of Science, and Technology (KAUST) Thuwal 23955-6900 Makkah Province Saudi Arabia.

出版信息

IEEE Open J Eng Med Biol. 2020 Aug 26;1:249-256. doi: 10.1109/OJEMB.2020.3019758. eCollection 2020.

Abstract

Coronavirus disease (COVID-19) is a contagious disease caused by a newly discovered coronavirus, initially identified in the mainland of China, late December 2019. COVID-19 has been confirmed as a higher infectious disease that can spread quickly in a community population depending on the number of susceptible and infected cases and also depending on their movement in the community. Since January 2020, COVID-19 has reached out to many countries worldwide, and the number of daily cases remains to increase rapidly. Several mathematical and statistical models have been developed to understand, track, and forecast the trend of the virus spread. model is one of the most promising epidemiological models that has been suggested for estimating the transmissibility of the COVID-19. In the present study, we propose a fractional-order SEIQRDP model to analyze the COVID-19 pandemic. In the recent decade, it has proven that many aspects in many domains can be described very successfully using fractional order differential equations. Accordingly, the Fractional-order paradigm offers a flexible, appropriate, and reliable framework for pandemic growth characterization. In fact, due to its non-locality properties, a fractional-order operator takes into consideration the variables' memory effect, and hence, it takes into account the sub-diffusion process of confirmed and recovered cases. The validation of the studied fractional-order model using real COVID-19 data for different regions in China, Italy, and France show the potential of the proposed paradigm in predicting and understanding the pandemic dynamic. Fractional-order epidemiological models might play an important role in understanding and predicting the spread of the COVID-19, also providing relevant guidelines for controlling the pandemic.

摘要

冠状病毒病(COVID-19)是一种由新发现的冠状病毒引起的传染病,最初于2019年12月下旬在中国内地被发现。COVID-19已被确认为一种传染性较强的疾病,它能够在社区人群中迅速传播,传播速度取决于易感病例和感染病例的数量,也取决于他们在社区中的活动情况。自2020年1月以来,COVID-19已蔓延至全球许多国家,每日新增病例数仍在迅速增加。已经开发了几种数学和统计模型来理解、追踪和预测病毒传播的趋势。[具体模型名称]模型是为估计COVID-19的传播性而提出的最有前景的流行病学模型之一。在本研究中,我们提出了一个分数阶SEIQRDP模型来分析COVID-19大流行。在最近十年中,已经证明在许多领域的许多方面都可以非常成功地用分数阶微分方程来描述。因此,分数阶范式为大流行增长特征提供了一个灵活、合适且可靠的框架。事实上,由于其非局部性特性,分数阶算子考虑了变量的记忆效应,因此,它考虑了确诊病例和康复病例的亚扩散过程。使用中国、意大利和法国不同地区的实际COVID-19数据对所研究的分数阶模型进行验证,结果表明所提出的范式在预测和理解大流行动态方面具有潜力。分数阶流行病学模型可能在理解和预测COVID-19的传播方面发挥重要作用,也为控制大流行提供相关指导方针。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d32b/8977216/80fd6dc9e854/laleg1-3019758.jpg

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