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肠菌素:分类、合成、抗菌机制和食品应用。

Enterocins: Classification, Synthesis, Antibacterial Mechanisms and Food Applications.

机构信息

Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, China.

College of Agriculture and Forestry, Linyi University, Linyi 276005, China.

出版信息

Molecules. 2022 Mar 30;27(7):2258. doi: 10.3390/molecules27072258.

DOI:10.3390/molecules27072258
PMID:35408657
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9000605/
Abstract

Enterococci, a type of lactic acid bacteria, are widely distributed in various environments and are part of the normal flora in the intestinal tract of humans and animals. Although enterococci have gradually evolved pathogenic strains causing nosocomial infections in recent years, the non-pathogenic strains have still been widely used as probiotics and feed additives. can produce enterocin, which are bacteriocins considered as ribosomal peptides that kill or inhibit the growth of other microorganisms. This paper reviews the classification, synthesis, antibacterial mechanisms and applications of enterocins, and discusses the prospects for future research.

摘要

肠球菌是一种乳酸菌,广泛分布于各种环境中,是人类和动物肠道正常菌群的一部分。近年来,肠球菌逐渐演化出了引起医院感染的致病性菌株,但非致病性菌株仍被广泛用作益生菌和饲料添加剂。肠球菌可以产生肠球菌素,这是一种被认为是核糖体肽的细菌素,可以杀死或抑制其他微生物的生长。本文综述了肠球菌的分类、合成、抗菌机制及其应用,并探讨了其未来的研究前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a16/9000605/7ecb08823dc6/molecules-27-02258-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a16/9000605/b73b67d1f512/molecules-27-02258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a16/9000605/7ecb08823dc6/molecules-27-02258-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a16/9000605/b73b67d1f512/molecules-27-02258-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a16/9000605/7ecb08823dc6/molecules-27-02258-g002.jpg

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Enterocins: Classification, Synthesis, Antibacterial Mechanisms and Food Applications.肠菌素:分类、合成、抗菌机制和食品应用。
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2
Mining, heterologous expression, purification, antibactericidal mechanism, and application of bacteriocins: A review.细菌素的挖掘、异源表达、纯化、抗菌机制及应用:综述
Compr Rev Food Sci Food Saf. 2021 Jan;20(1):863-899. doi: 10.1111/1541-4337.12658. Epub 2020 Oct 29.
3
Antimicrobial activity of enterocins against Listeria sp. and other food spoilage bacteria.
揭示肠球菌属的益生菌潜力:动物和人类健康中的机制与作用,全面综述
World J Microbiol Biotechnol. 2025 Jun 25;41(7):214. doi: 10.1007/s11274-025-04389-5.
4
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Sci Rep. 2025 Feb 9;15(1):4846. doi: 10.1038/s41598-025-89518-8.
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Isolation of Enterococcus hirae From Fresh White Yak Milk in Ledu District, Qinghai Province, China: A Comparative Genomic Analysis.从中国青海省乐都区新鲜白牦牛乳中分离出平肠球菌:比较基因组分析
Curr Microbiol. 2025 Feb 3;82(3):111. doi: 10.1007/s00284-024-04044-6.
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