Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, Jiangsu Ocean University, Lianyungang 222005, China.
Jiangsu Key Laboratory of Marine Biotechnology, School of Food Science and Engineering, Jiangsu Ocean University, Lianyungang 222005, China.
Mar Drugs. 2022 Mar 28;20(4):230. doi: 10.3390/md20040230.
Antibiotic resistance and residues in aquaculture are a growing concern worldwide and consequently identifying favorable antibacterial compounds against aquatic pathogenic bacteria are gained more attention. Active compounds derived from marine microorganisms have shown great promise in this area. This review is aimed to make a comprehensive survey of anti-aquatic pathogenic bacterial compounds that were produced by marine microorganisms. A total of 79 compounds have been reported, covering literature from 1997 to 2021. The compounds are included in different structural classes such as polyketides, terpenoids, nitrogen compounds and others, and some of them present the potential to be developed into agents for the treatment of aquatic pathogenic bacteria.
抗生素耐药性和水产养殖中的残留问题是全球日益关注的问题，因此，寻找针对水生致病菌的有利抗菌化合物受到了更多关注。海洋微生物来源的活性化合物在这一领域显示出巨大的前景。本综述旨在全面调查海洋微生物产生的抗水生致病菌化合物。共报道了 79 种化合物，涵盖了 1997 年至 2021 年的文献。这些化合物包括不同的结构类别，如聚酮类、萜类、含氮化合物等，其中一些具有开发为治疗水生致病菌的药物的潜力。
