Institute of Molecular Biology and Biotechnology, FORTH, 71110 Heraklion, Greece.
Enzyme and Microbial Biotechnology Unit, Faculty of Biology, National and Kapodistrian University of Athens, Zografou, 15784 Athens, Greece.
Int J Mol Sci. 2022 Apr 7;23(8):4080. doi: 10.3390/ijms23084080.
Copper-based bactericides have appeared as a new tool in crop protection and offer an effective solution to combat bacterial resistance. In this work, two copper nanoparticle products that were previously synthesized and evaluated against major bacterial and fungal pathogens were tested on their ability to control the bacterial spot disease of tomato. Growth of pv. , the causal agent of the disease, was significantly suppressed by both nanoparticles, which had superior function compared to conventional commercial formulations of copper. X-ray fluorescence spectrometry measurements in tomato leaves revealed that bioavailability of copper is superior in the case of nanoparticles compared to conventional formulations and is dependent on synthesis rather than size. This is the first report correlating bioavailability of copper to nanoparticle efficacy.
铜基杀菌剂作为作物保护的一种新工具出现，为应对细菌抗药性提供了有效的解决方案。在这项工作中，我们对之前合成并针对主要细菌和真菌病原体进行评估的两种铜纳米颗粒产品进行了测试，以评估它们控制番茄细菌性斑点病的能力。这两种纳米颗粒都显著抑制了 pv. 的生长，这种病原体是这种疾病的致病因子，与传统的铜商业制剂相比，它们具有更好的功能。在番茄叶片中的 X 射线荧光光谱测量表明，与传统制剂相比，纳米颗粒中的铜的生物利用度更高，并且这取决于合成而不是大小。这是首次将铜的生物利用度与纳米颗粒功效相关联的报道。
