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聚合物涂层和抗菌肽作为治疗植入式医疗器械相关感染的有效系统。

Polymeric Coatings and Antimicrobial Peptides as Efficient Systems for Treating Implantable Medical Devices Associated-Infections.

作者信息

Negut Irina, Bita Bogdan, Groza Andreea

机构信息

National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Street, Magurele, 077125 Bucharest, Romania.

出版信息

Polymers (Basel). 2022 Apr 15;14(8):1611. doi: 10.3390/polym14081611.

Abstract

Many infections are associated with the use of implantable medical devices. The excessive utilization of antibiotic treatment has resulted in the development of antimicrobial resistance. Consequently, scientists have recently focused on conceiving new ways for treating infections with a longer duration of action and minimum environmental toxicity. One approach in infection control is based on the development of antimicrobial coatings based on polymers and antimicrobial peptides, also termed as "natural antibiotics".

摘要

许多感染与植入式医疗设备的使用有关。抗生素治疗的过度使用导致了抗菌耐药性的产生。因此,科学家们最近专注于构思新的治疗感染的方法,这些方法具有更长的作用时间和最小的环境毒性。感染控制的一种方法是基于开发基于聚合物和抗菌肽的抗菌涂层,也被称为“天然抗生素”。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/667b/9024559/4b216dc23ea7/polymers-14-01611-g001.jpg

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