原位肝移植的临床考量

Clinical considerations in orthotopic liver transplantation.

作者信息

Tzakis A G, Gordon R D, Makowka L, Esquivel C O, Todo S, Iwatsuki S, Starzl T E

出版信息

Radiol Clin North Am. 1987 Mar;25(2):289-97.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2965559/

Abstract

Progress in immunosuppression, surgical techniques, and perioperative care has promoted orthotopic liver transplantation from an experimental procedure to an accepted clinical treatment. Orthotopic liver transplantation, in turn, has changed the treatment of terminal liver disease from care that is largely treatment of symptoms and support to cure, but at the price of major surgery and life-long immunosuppression. This article reviews the current status of liver transplantation as practiced at the University of Pittsburgh.

摘要

免疫抑制、手术技术和围手术期护理方面的进展，已将原位肝移植从一种实验性手术推进为一种被认可的临床治疗方法。反过来，原位肝移植也改变了终末期肝病的治疗方式，从主要是对症治疗和支持治疗转变为可治愈，但代价是大手术和终身免疫抑制。本文回顾了匹兹堡大学目前开展肝移植的现状。

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Clinical considerations in orthotopic liver transplantation.原位肝移植的临床考量

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本文引用的文献

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ORTHOCLONE OKT3 in Treatment of Allografts Rejected Under Cyclosporine-Steroid Therapy.Orthoclone OKT3用于治疗在环孢素-类固醇疗法下被排斥的同种异体移植物。

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Orthotopic Liver Transplantation in Children With Hepatic-Based Metabolic Disease.患有肝脏基础代谢疾病儿童的原位肝移植

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Evolution of liver transplantation.肝移植的发展历程。

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Isohemagglutinins of graft origin after ABO-unmatched liver transplantation.ABO血型不匹配肝移植后移植物来源的同种血凝素

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Heart-liver transplantation in a patient with familial hypercholesterolaemia.家族性高胆固醇血症患者的心脏-肝脏移植

Lancet. 1984 Jun 23;1(8391):1382-3. doi: 10.1016/s0140-6736(84)91876-2.

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Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy.在环孢素-类固醇治疗下发生的淋巴瘤和淋巴增殖性病变的可逆性。

Lancet. 1984 Mar 17;1(8377):583-7. doi: 10.1016/s0140-6736(84)90994-2.

10

Liver transplantation in a hemophiliac.血友病患者的肝移植

N Engl J Med. 1985 May 2;312(18):1189-90. doi: 10.1056/NEJM198505023121812.

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