Fatima Ifrah, Jahagirdar Vinay, Kulkarni Anand V, Reddy Raghuram, Sharma Mithun, Menon Balchandran, Reddy Duvvur Nageshwar, Rao Padaki Nagaraja
University of Missouri-Kansas City School of Medicine, MO, USA.
Department of Hepatology, AIG Hospitals, Hyderabad, India.
J Clin Exp Hepatol. 2023 Sep-Oct;13(5):841-853. doi: 10.1016/j.jceh.2023.04.002. Epub 2023 Apr 17.
Liver transplantation (LT) is the definitive therapy for patients with end-stage liver disease, acute liver failure, acute-on-chronic liver failure, hepatocellular carcinoma, and metabolic liver diseases. The acceptance of LT in Asia has been gradually increasing and so is the expertise to perform LT. Preparing a patient with cirrhosis for LT is the most important aspect of a successful LT. The preparation for LT begins with the first index decompensation for a patient with cirrhosis. Patients planned for LT should undergo a thorough screening for infections, and a complete cardiac, pulmonology, and psychosocial evaluation pre-LT. In this review, we discuss the indications and contraindications of LT and the evaluation and assessment of patients with liver disease planned for LT.
肝移植(LT)是终末期肝病、急性肝衰竭、慢加急性肝衰竭、肝细胞癌和代谢性肝病患者的确定性治疗方法。在亚洲,肝移植的接受度一直在逐渐提高,实施肝移植的专业技术也在不断提升。为肝硬化患者进行肝移植准备是成功进行肝移植的最重要环节。肝移植准备工作始于肝硬化患者首次出现失代偿。计划接受肝移植的患者应在肝移植前接受全面的感染筛查以及完整的心脏、肺部和社会心理评估。在本综述中,我们讨论了肝移植的适应证和禁忌证以及计划接受肝移植的肝病患者的评估。