School of Biomedical Engineering (Suzhou), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China; Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, China.
Department of Cardiology, Children's Hospital of Soochow University, Suzhou, 215003, China.
Comput Biol Med. 2022 Jul;146:105545. doi: 10.1016/j.compbiomed.2022.105545. Epub 2022 Apr 20.
Accurate skin lesion segmentation plays a fundamental role in computer-aided melanoma analysis. Recently, some FCN-based methods have been proposed and achieved promising results in lesion segmentation tasks. However, due to the variable shapes, different scales, noise interference, and ambiguous boundaries of skin lesions, the capabilities of lesion location and boundary delineation of these works are still insufficient. To overcome the above challenges, in this paper, we propose a novel Neighborhood Context Refinement Network (NCRNet) by using the coarse-to-fine strategy to achieve accurate skin lesion segmentation. The proposed NCRNet contains a shared encoder and two different but closely related decoders for locating the skin lesions and refining the lesion boundaries. Specifically, we first design the Parallel Attention Decoder (PAD), which can effectively extract and fuse the local detail information and global semantic information on multiple levels to locate skin lesions of different sizes and shapes. Then, based on the initial lesion location, we further design the Neighborhood Context Refinement Decoder (NCRD), aiming at leveraging the fine-grained multi-stage neighborhood context cues to refine the lesion boundaries continuously. Furthermore, the neighborhood-based deep supervision used in the NCRD can make the shared encoder pay more attention to the lesion boundary areas and promote convergence of the segmentation network. The public skin lesion segmentation dataset ISIC2017 is adopted to validate the effectiveness of the proposed NCRNet. Comprehensive experiments prove that the proposed NCRNet reaches the state-of-the-art performance than the other nine competitive methods and gets 78.62%, 86.55%, and 94.01% on Jaccard, Dice, and Accuracy, respectively.
准确的皮肤病变分割在计算机辅助黑色素瘤分析中起着至关重要的作用。最近,一些基于 FCN 的方法被提出,并在病变分割任务中取得了有希望的结果。然而,由于皮肤病变的形状多变、尺度不同、噪声干扰和边界模糊,这些工作的病变定位和边界描绘能力仍然不足。为了克服上述挑战,本文提出了一种新的基于邻域上下文细化网络(NCRNet)的方法,该方法采用由粗到精的策略实现精确的皮肤病变分割。所提出的 NCRNet 包含一个共享编码器和两个不同但密切相关的解码器,用于定位皮肤病变和细化病变边界。具体来说,我们首先设计了并行注意力解码器(PAD),它可以有效地提取和融合多个层次的局部细节信息和全局语义信息,从而定位不同大小和形状的皮肤病变。然后,基于初始病变位置,我们进一步设计了邻域上下文细化解码器(NCRD),旨在利用精细的多阶段邻域上下文线索来连续细化病变边界。此外,NCRD 中使用的基于邻域的深度监督可以使共享编码器更加关注病变边界区域,并促进分割网络的收敛。我们采用公共皮肤病变分割数据集 ISIC2017 来验证所提出的 NCRNet 的有效性。综合实验证明,与其他 9 种竞争方法相比,所提出的 NCRNet 具有更好的性能,在 Jaccard、Dice 和 Accuracy 上分别达到了 78.62%、86.55%和 94.01%。