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活细胞上的纳米结构学

Nanoarchitectonics on living cells.

作者信息

Ariga Katsuhiko, Fakhrullin Rawil

机构信息

WPI Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS) 1-1 Namiki Tsukuba Ibaraki 305-0044 Japan

Graduate School of Frontier Sciences, The University of Tokyo 5-1-5 Kashiwanoha Kashiwa Chiba 277-8561 Japan.

出版信息

RSC Adv. 2021 May 25;11(31):18898-18914. doi: 10.1039/d1ra03424c. eCollection 2021 May 24.

Abstract

In this review article, the recent examples of nanoarchitectonics on living cells are briefly explained. Not limited to conventional polymers, functional polymers, biomaterials, nanotubes, nanoparticles (conventional and magnetic ones), various inorganic substances, metal-organic frameworks (MOFs), and other advanced materials have been used as components for nanoarchitectonic decorations for living cells. Despite these artificial processes, the cells can remain active or remain in hibernation without being killed. In most cases, basic functions of the cells are preserved and their resistances against external assaults are much enhanced. The possibilities of nanoarchitectonics on living cells would be high, equal to functional modifications with conventional materials. Living cells can be regarded as highly functionalized objects and have indispensable contributions to future materials nanoarchitectonics.

摘要

在这篇综述文章中,简要解释了近期在活细胞上进行纳米结构构建的实例。不限于传统聚合物,功能聚合物、生物材料、纳米管、纳米颗粒(传统的和磁性的)、各种无机物、金属有机框架(MOF)以及其他先进材料都已被用作活细胞纳米结构修饰的组件。尽管有这些人工操作过程,但细胞仍可保持活性或处于休眠状态而不被杀死。在大多数情况下,细胞的基本功能得以保留,并且它们抵御外部攻击的能力大大增强。在活细胞上进行纳米结构构建的可能性很高,等同于用传统材料进行功能修饰。活细胞可被视为高度功能化的对象,对未来材料的纳米结构构建有着不可或缺的贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4f0/9033578/b110a9f3ef1e/d1ra03424c-f1.jpg

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