Yang Liu, Zhang Jiaxu, Zheng Senwang, Hou Ajiao, Wang Song, Yu Huan, Wang Xuejiao, Xu Yingjie, Kuang Haixue, Jiang Hai
Key Laboratory of Chinese Materia Medica, Ministry of Education, Heilongjiang University of Chinese Medicine Harbin 150040 China
RSC Adv. 2021 May 27;11(31):19221-19237. doi: 10.1039/d1ra01366a. eCollection 2021 May 24.
is a Chinese herb, which has been used in China for thousands of years, mainly for the treatment of nephrolithiasis. This paper summarizes the modern research progress on from the aspects of botany, traditional medicinal use, phytochemistry, pharmacology, pharmacokinetics, analytical methods and quality control. In addition, it also points out the deficiencies of current research on this herb and provides possible directions for its development. So far, more than 190 chemical components have been isolated and identified from , including organic acids and their esters, volatile oils, flavonoids and their glycosides, terpenes and other chemical components. Its extracts and compounds have a wide range of pharmacological effects, including anti-stone, anti-inflammatory, bacteriostatic, cholagogic and diuretic, effect on ileum smooth muscle, anti-tumor effect on tumor and hypoglycemic effects. However, future studies should focus on drug metabolism, clarify its pharmacodynamic mechanism, and establish a reasonable quality control standards for .
是一种中草药,在中国已使用了数千年,主要用于治疗肾结石。本文从植物学、传统药用、植物化学、药理学、药代动力学、分析方法和质量控制等方面总结了关于的现代研究进展。此外,还指出了目前对该草药研究的不足,并为其发展提供了可能的方向。迄今为止,已从分离鉴定出190多种化学成分,包括有机酸及其酯类、挥发油、黄酮类及其糖苷、萜类等化学成分。其提取物和化合物具有广泛的药理作用,包括抗结石、抗炎、抑菌、利胆和利尿、对回肠平滑肌的作用、对肿瘤的抗肿瘤作用和降血糖作用。然而,未来的研究应集中在药物代谢上,阐明其药效机制,并为建立合理的质量控制标准。
需注意,原文中“from the aspects of botany, traditional medicinal use, phytochemistry, pharmacology, pharmacokinetics, analytical methods and quality control. In addition, it also points out the deficiencies of current research on this herb and provides possible directions for its development. So far, more than 190 chemical components have been isolated and identified from ”这里的“from”后缺少具体所指的草药名称,我按照最常规理解进行了翻译,但从语法角度看不太完整。