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Environ Sci Technol Lett. 2020 May 18;7(7):477-481. doi: 10.1021/acs.estlett.0c00323.
2
Occurrence of Per- and Polyfluoroalkyl Substances (PFAS) in Source Water and Their Treatment in Drinking Water.源水中全氟和多氟烷基物质（PFAS）的存在及其在饮用水中的处理
Crit Rev Environ Sci Technol. 2019 Jun;49(24):2359-2396. doi: 10.1080/10643389.2019.1614848.
3
Determinants of serum concentrations of perfluoroalkyl acids (PFAAs) in school children and the contribution of low-level PFAA-contaminated drinking water.儿童血清中全氟烷基酸（PFAAs）浓度的决定因素以及低水平 PFAA 污染饮用水的贡献。
Environ Sci Process Impacts. 2020 Apr 29;22(4):930-944. doi: 10.1039/c9em00497a.
4
Aerobic biotransformation of fluorotelomer compounds in landfill leachate-sediment.在垃圾渗滤液-沉积物中氟调聚物的好氧生物转化。
Sci Total Environ. 2020 Apr 15;713:136547. doi: 10.1016/j.scitotenv.2020.136547. Epub 2020 Jan 10.
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First Report on In Vivo Pharmacokinetics and Biotransformation of Chlorinated Polyfluoroalkyl Ether Sulfonates in Rainbow Trout.首例关于氯代多氟烷基醚磺酸盐在虹鳟鱼体内药代动力学和生物转化的报告。
Environ Sci Technol. 2020 Jan 7;54(1):345-354. doi: 10.1021/acs.est.9b05258. Epub 2019 Dec 12.
6
The oxidation of cysteine-containing peptides caused by perfluoroalkane sulfonyl fluorides.含半胱氨酸肽的过氟烷磺酰氟氧化。
J Hazard Mater. 2020 Mar 5;385:121564. doi: 10.1016/j.jhazmat.2019.121564. Epub 2019 Nov 7.
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Biotransformation of 6:2 fluorotelomer alcohol by the whole soybean (Glycine max L. Merrill) seedlings.全大豆（Glycine max L. Merrill）幼苗对 6:2 氟调聚物醇的生物转化。
Environ Pollut. 2020 Feb;257:113513. doi: 10.1016/j.envpol.2019.113513. Epub 2019 Oct 31.
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An investigation into per- and polyfluoroalkyl substances (PFAS) in nineteen Australian wastewater treatment plants (WWTPs).对澳大利亚19家污水处理厂中的全氟和多氟烷基物质（PFAS）进行的一项调查。
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Spatial and Interspecies Heterogeneity in Concentrations of Perfluoroalkyl Substances (PFASs) in Seabirds of the Southern Ocean.南大洋海鸟体内全氟烷基物质（PFAS）浓度的空间和种间异质性。
Environ Sci Technol. 2019 Aug 20;53(16):9855-9865. doi: 10.1021/acs.est.9b02677. Epub 2019 Aug 6.
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开发全氟和多氟烷基物质反应库：鉴定环境和生物系统中可能的转化途径。

Development of a PFAS reaction library: identifying plausible transformation pathways in environmental and biological systems.

机构信息

Center for Environmental Measurement and Modeling, United States Environmental Protection Agency, Athens, Georgia 30605, USA.

Oak Ridge Institute for Science and Education (ORISE), Hosted at U.S. Environmental Protection Agency, Athens, Georgia 30605, USA.

出版信息

Environ Sci Process Impacts. 2022 May 25;24(5):689-753. doi: 10.1039/d1em00445j.

DOI:10.1039/d1em00445j
PMID:35485941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9361427/
Abstract

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are used in many consumer applications due to their stain repellency, surfactant properties, ability to form water-proof coatings and use in fire suppression. The production, application, transport, use and disposal of PFAS and PFAS-treated products have resulted in their wide-spread occurrence in environmental and biological systems. Concern over exposure to PFAS and their transformation products and metabolites has necessitated the development of tools to predict the transformation of PFAS in environmental systems and metabolism in biological systems. We have developed reaction libraries for predicting transformation products and metabolites in a variety of environmental and biological reaction systems. These reaction libraries are based on generalized reaction schemes that encode the process science of PFAS reported in the peer-reviewed literature. The PFAS reaction libraries will be executed through the Chemical Transformation Simulator, a web-based tool that is available to the public. These reaction libraries are intended for predicting the environmental transformation and metabolism of PFAS only.

摘要

全氟烷基和多氟烷基物质（PFAS）由于其抗污渍、表面活性剂特性、形成防水涂层的能力以及在灭火中的应用，被广泛应用于许多消费产品中。PFAS 和经过 PFAS 处理的产品的生产、应用、运输、使用和处置导致其在环境和生物系统中广泛存在。由于担心接触 PFAS 及其转化产物和代谢物，因此需要开发工具来预测 PFAS 在环境系统中的转化和在生物系统中的代谢。我们已经开发了反应库，用于预测各种环境和生物反应系统中的转化产物和代谢物。这些反应库基于广义的反应方案，该方案编码了同行评议文献中报道的 PFAS 的过程科学。PFAS 反应库将通过 Chemical Transformation Simulator 执行，这是一个可供公众使用的基于网络的工具。这些反应库仅用于预测 PFAS 的环境转化和代谢。