用于评估洗手液的光谱方法。

Spectroscopic methods for assessment of hand sanitizers.

作者信息

Banik Soumyabrata, Melanthota Sindhoora Kaniyala, Vannathan Anjana Anandan, Mahato Krishna Kishore, Mal Sib Sankar, Mazumder Nirmal

机构信息

Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka 576104 India.

Materials and Catalysis Lab, Department of Chemistry, National Institute of Technology Karnataka, Surathkal, Karnataka 575025 India.

出版信息

Chem Zvesti. 2022;76(8):4907-4918. doi: 10.1007/s11696-022-02208-x. Epub 2022 Apr 25.

DOI:10.1007/s11696-022-02208-x

PMID:35492072

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9035981/

Abstract

UNLABELLED

Sanitization of inanimate objects or body surfaces using disinfectant is essential for eliminating disease-causing pathogens and maintaining personal hygiene. With the advent of health emergencies, the importance and high demand for hand sanitizers (HS) are observed in everyday life. It is also important to know the constituent added to formulate HS, as the presence of harsh chemicals can cause skin irritation. In this study, different spectroscopic techniques were used to assess several commercially available HS along with the in-house prepared HS as per the WHO protocol. Fourier transform infrared spectroscopy and Raman spectroscopy identified the different HS chemical bonds and quantified the amount of alcohol and water in the HS. Varying amount of alcohols in HS, calibration profile was generated to identify its amount in commercial samples. Further, the commercial samples were also checked for contaminants whose presence in the HS might bring down its sanitization efficacy.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s11696-022-02208-x.

摘要

未标注

使用消毒剂对无生命物体或身体表面进行消毒对于消除致病病原体和保持个人卫生至关重要。随着健康紧急情况的出现，日常生活中对手部消毒剂（HS）的重要性和高需求日益凸显。了解用于配制HS的成分也很重要，因为存在刺激性化学物质可能会导致皮肤过敏。在本研究中，根据世界卫生组织的方案，使用了不同的光谱技术来评估几种市售的HS以及内部制备的HS。傅里叶变换红外光谱和拉曼光谱确定了不同HS的化学键，并对HS中的酒精和水的含量进行了定量。针对HS中不同含量的酒精，生成了校准曲线以确定其在商业样品中的含量。此外，还对商业样品中的污染物进行了检测，这些污染物在HS中的存在可能会降低其消毒效果。