Benvenutti Laís, Zielinski Acácio Antonio Ferreira, Ferreira Sandra Regina Salvador
Chemical and Food Engineering Department, Federal University of Santa Catarina, Florianópolis, SC, C.P. 476, 88040-900, Brazil.
Food Chem X. 2022 Feb 1;13:100236. doi: 10.1016/j.fochx.2022.100236. eCollection 2022 Mar 30.
Deep eutectic solvents (DES) are emergent solvents with high extractability of bioactive compounds. Therefore, anthocyanin rich-fractions were recovered from jaboticaba peels by combining aqueous solutions of DES and pressurized liquid extraction (PLE). The extraction occurred at 10 MPa, 12 min, with conditions optimized through response surface methodology: 47% DES concentration, 90 °C, and 5.3 mL/min flow rate. PLE with different DES (choline chloride combined with propylene glycol or malic acid) solutions were compared to conventional solvents (water and acidified water) concerning yield, thermostability, antioxidant, anti-diabetic, and anti-obesity activities. DES solutions presented anthocyanin yields up to 50% higher than conventional solvents. ChCl:Ma, with the highest anthocyanin stability ( = 77.5 kJ.mol), was a promising solvent concerning color, anti-diabetic and anti-obesity potential. Environmental analysis by and indicated PLE with DES solutions is a green and efficient approach to recover anthocyanin from jaboticaba peel, providing useful extracts.
深共熔溶剂（DES）是一类新型溶剂，对生物活性化合物具有高萃取能力。因此，通过将DES水溶液与加压液体萃取（PLE）相结合，从巴西葡萄果皮中回收了富含花青素的组分。萃取在10兆帕、12分钟的条件下进行，通过响应面法优化条件为：DES浓度47%、90℃、流速5.3毫升/分钟。将不同DES（氯化胆碱与丙二醇或苹果酸组合）溶液的PLE与传统溶剂（水和酸化水）在产量、热稳定性、抗氧化、抗糖尿病和抗肥胖活性方面进行了比较。DES溶液的花青素产量比传统溶剂高出50%。ChCl:Ma具有最高的花青素稳定性（ = 77.5千焦·摩尔），在颜色、抗糖尿病和抗肥胖潜力方面是一种有前景的溶剂。 和 的环境分析表明，用DES溶液进行PLE是从巴西葡萄果皮中回收花青素的一种绿色高效方法，可提供有用的提取物。
