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儿童时期奶酪摄入量与 LDL 胆固醇呈负相关。

Cheese Intake is Inversely Associated with LDL Cholesterol in Young Children.

机构信息

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON.

Department of Family Relations and Applied Nutrition, University of Guelph, Guelph, ON.

出版信息

Can J Diet Pract Res. 2022 Dec 1;83(4):208-211. doi: 10.3148/cjdpr-2022-012. Epub 2022 May 3.

Abstract

To determine if intake (servings/day) of total dairy and/or dairy subtypes (milk, cheese, and yogurt) were associated with biomarkers related to dyslipidemia, insulin sensitivity and inflammation in a sample of cardio-metabolically healthy young children from the Guelph Family Health Study at the University of Guelph, Guelph, Ontario, Canada. Baseline data from 42 children (aged 2.0-6.2 years) from 33 families who provided a dietary assessment and a fasted blood sample were included in this cross-sectional analysis. Linear and logistic regressions using generalized estimating equations were used for analysis and models were adjusted for age, gender, and household income. In total, 42 children (3.74 ± 1.23 years old; mean (± SD)) consumed median (25th percentile, 75th percentile) servings/day of 1.70 (1.16, 2.81) for total dairy, 0.74 (0.50, 1.70) for milk, 0.63 (0.00, 1.16) for cheese, and 0.00 (0.00, 0.38) for yogurt. Cheese intake was significantly inversely associated with LDL cholesterol (-0.16 (95% CI: -0.29, -0.03) mmol/L per serving;  = 0.02)). No other associations between dairy intake and biomarkers were significant. Cheese intake was inversely associated with LDL cholesterol in this preliminary study of cardio-metabolically healthy young children, thereby warranting further research on dairy intake and cardiometabolic risk factors.

摘要

为了确定在安大略省圭尔夫大学圭尔夫家庭健康研究中,代谢健康的年轻儿童样本中,总乳制品和/或乳制品亚类(牛奶、奶酪和酸奶)的摄入量(份/天)是否与血脂异常、胰岛素敏感性和炎症相关的生物标志物有关。本横断面分析纳入了来自 33 个家庭的 42 名儿童(年龄 2.0-6.2 岁)的基线数据,这些儿童提供了饮食评估和空腹血样。使用广义估计方程的线性和逻辑回归用于分析,模型调整了年龄、性别和家庭收入。总共有 42 名儿童(3.74±1.23 岁;中位数(25 百分位数,75 百分位数)每天摄入的总乳制品量为 1.70(1.16,2.81)份,牛奶 0.74(0.50,1.70)份,奶酪 0.63(0.00,1.16)份,酸奶 0.00(0.00,0.38)份。奶酪摄入量与 LDL 胆固醇呈显著负相关(-0.16(95%CI:-0.29,-0.03)mmol/L/份;=0.02))。乳制品摄入量与生物标志物之间没有其他显著关联。在这项针对代谢健康的年轻儿童的初步研究中,奶酪摄入量与 LDL 胆固醇呈负相关,因此需要进一步研究乳制品摄入量与心血管代谢危险因素之间的关系。

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