Zhang Yuanfei, Huang Ting, Li Xinghua, Zhang Min, Song Ying, Huang Kelin, Su Weiping
Guangxi Key Laboratory of Natural Polymer Chemistry and Physics, Nanning Normal University Nanning 530001 China.
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences Fuzhou 350002 China
RSC Adv. 2020 Jun 10;10(37):22216-22221. doi: 10.1039/d0ra03348k. eCollection 2020 Jun 8.
The Rh(iii)-catalyzed synthesis of spiroquinoxalinone derivatives from 3-arylquinoxalin-2(1)-ones and alkynes a C-H functionalization/[3 + 2] annulation sequence has been developed. This method, featuring low catalyst loading, was amenable to Gram scale synthesis and tolerated a variety of functional groups and substitution patterns on the aryl rings, providing the target products in good to excellent yields.
已开发出一种由铑（III）催化的、从3-芳基喹喔啉-2（1）-酮和炔烃合成螺喹喔啉酮衍生物的方法，该方法是一种C-H官能团化/[3+2]环化序列。此方法催化剂负载量低，适用于克级规模的合成，并且能耐受芳环上的各种官能团和取代模式，以良好至优异的产率提供目标产物。
