KSO促进碳硒键形成以构建α-苯硒基羰基化合物和α,β-不饱和羰基化合物。
KSO-promoted C-Se bond formation to construct α-phenylseleno carbonyl compounds and α,β-unsaturated carbonyl compounds.
作者信息
Yang Xue-Yan, Wang Ruizhe, Wang Lu, Li Jianjun, Mao Shuai, Zhang San-Qi, Chen Nanzheng
机构信息
Department of Medicinal Chemistry, School of Pharmacy, Xi'an Jiaotong University Xi'an Shaanxi 710061 PR China
Department of Chemistry, School of Science, MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiaotong University Xi'an Shaanxi 710049 PR China.
出版信息
RSC Adv. 2020 Aug 5;10(48):28902-28905. doi: 10.1039/d0ra05927g. eCollection 2020 Aug 3.
A novel KSO-promoted C-Se bond formation from cross-coupling under neutral conditions has been developed. A variety of aldehydes and ketones react well using KSO as the oxidant in the absence of catalyst and afford desired products in moderate to excellent yields. This protocol provides a very simple route for the synthesis of α-phenylseleno carbonyl compounds and α,β-unsaturated carbonyl compounds.
已开发出一种新型的在中性条件下通过交叉偶联由KSO促进形成C-Se键的方法。在无催化剂的情况下，使用KSO作为氧化剂，多种醛和酮反应良好，并以中等至优异的产率得到所需产物。该方法为合成α-苯硒基羰基化合物和α,β-不饱和羰基化合物提供了一条非常简单的途径。
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