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来自马铃薯内生真菌的抗植物病原倍半萜-呫吨酮加合物

Anti-phytopathogenic sesquiterpenoid-xanthone adducts from potato endophytic fungus .

作者信息

He Juan, Yang Man-Si, Wang Wen-Xiang, Li Zheng-Hui, Elkhateeb Waill Ahmed Mohamed, Wen Ting-Chi, Ai Hong-Lian, Feng Tao

机构信息

School of Pharmaceutical Sciences, South-Central University for Nationalities Wuhan 430074 China

School of Agriculture and Biological Technic, Yunnan Agricultural University Kunming 650201 China.

出版信息

RSC Adv. 2018 Dec 21;9(1):128-131. doi: 10.1039/c8ra09861a. eCollection 2018 Dec 19.

Abstract

A bioguided separation on the cultures of the potato endophytic fungus led to the isolation of two anti-phytopathogenic () sesquiterpenoid-xanthone adducts, namely bipolins I and J (1 and 2). Their structures were established extensive spectroscopic analysis. Compounds 1 and 2 exhibit potent inhibitory activity against with MIC values of 8 and 16 μg mL, respectively.

摘要

对马铃薯内生真菌培养物进行生物导向分离,得到了两种抗植物病原菌的倍半萜-呫吨酮加合物,即双孢菌素I和J(1和2)。通过广泛的光谱分析确定了它们的结构。化合物1和2对[具体植物病原菌未给出]表现出强效抑制活性,其最低抑菌浓度(MIC)值分别为8和16μg/mL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aceb/9059304/3b3bd0400004/c8ra09861a-f1.jpg

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