Pediatric Ophthalmology and Strabismus Department, Tianjin Eye Hospital, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin, China.
School of Electronic Information Engineering, Tianjin University, Tianjin, China.
Invest Ophthalmol Vis Sci. 2022 May 2;63(5):7. doi: 10.1167/iovs.63.5.7.
The purpose of this study was to investigate the cortical electrical activity and electroencephalography (EEG) features of the frontal lobe evoked by dynamic random dot stereogram (DRDS) and to probe the functional connectivity (FC) between the frontal lobe and occipital lobe when processing 3D perception based on the binocular disparity.
The EEG experiment involved 14 healthy adults with normal stereopsis (<60″) and normal corrected visual acuity (20/20). The Neuroscan system and 32-channel EEG cap were used to record EEG signals based on the DRDS stimuli. The maximum energies of 3 frequency bands (theta-/alpha- /beta-wave) from 13 interesting channels (FP1, FP2, F7, F3, FZ, F4, F8, FC3, FCZ, FC4, O1, OZ, and O2) located in the frontal and occipital lobes were calculated and analyzed. The FC between any two electrodes from the frontal and occipital lobes was calculated based on the Phase lag index (PLI).
The maximum powers of theta- and alpha-waves in most channels of the frontal and occipital lobes were significantly increased (P < 0.05) when the depth perception was evoked by DRDS above the threshold, compared with that without stereo vision. The changes in the maximum powers of both theta- and alpha-waves were significantly different among the 13 electrodes (P = 0.0004 and 0.0015, respectively). Tukey's multiple comparisons showed that the changes in the maximum powers of theta-wave were significantly different in F8 vs. O1, F8 vs. OZ, and F4 vs. O1 (P = 0.0186, 0.0444, and 0.0412, respectively). Moreover, the changes in the maximum powers of alpha-waves were significantly different in FP1 vs. O1 (P = 0.0182). The FCs of theta-waves between the frontal channels and the occipital channels were significantly enhanced when processing the depth perception, compared with those without stereopsis. There was no significant change in the FCs of the alpha-waves when having 3D perception except for FC between F8 and O1 and FC between F8 and OZ.
The cortical electrical activity in the frontal lobe and the functional connectivity between the frontal lobe and the occipital lobe increase when participating in the processing binocular disparity and obtaining 3D perception. Theta-waves in the frontal lobe may be crucial in the stereo vision.
本研究旨在探讨动态随机点立体图（DRDS）诱发的额叶皮质电活动和脑电图（EEG）特征，并探究基于双眼视差处理三维感知时额叶与枕叶之间的功能连接（FC）。
本 EEG 实验纳入 14 名立体视正常（<60″）、矫正视力正常（20/20）的健康成年人。采用 Neuroscan 系统和 32 通道 EEG 帽，基于 DRDS 刺激记录 EEG 信号。计算并分析位于额叶和枕叶的 13 个感兴趣通道（FP1、FP2、F7、F3、FZ、F4、F8、FC3、FCZ、FC4、O1、OZ 和 O2）中 3 个频带（θ-/α-/β-波）的最大能量。基于相位滞后指数（PLI）计算额叶和枕叶任意两个电极之间的 FC。
与无立体视觉时相比，当 DRDS 刺激超过阈值诱发深度知觉时，额叶和枕叶大多数通道的θ波和α波最大功率均显著增加（P<0.05）。13 个电极中θ波和α波最大功率的变化均有显著差异（P=0.0004 和 0.0015）。Tukey 多重比较显示，θ波最大功率的变化在 F8 与 O1、F8 与 OZ 和 F4 与 O1 之间有显著差异（P=0.0186、0.0444 和 0.0412）。此外，α波最大功率的变化在 FP1 与 O1 之间有显著差异（P=0.0182）。与无立体视时相比，处理深度知觉时额叶通道与枕叶通道之间的θ波 FC 显著增强，而α波 FC 除 F8 与 O1 和 F8 与 OZ 之间外，无显著变化。
参与双眼视差处理和获得三维感知时，额叶皮质电活动增强，额叶与枕叶之间的功能连接增强。额叶中的θ波可能在立体视觉中起关键作用。
