Cho L K, Lowe J A, Maguire R B, Tsang J C
Experientia. 1987 Apr 15;43(4):397-9. doi: 10.1007/BF01940425.
Prodigiosin condensing enzyme (PCE) activities were present in Serratia marcescens wild type 08, mutants OF, WF and 9-3-3. Their specific activities exhibited different maxima and at different times during the late log phase or the early stationary phase of cell growth. The levels of prodigiosin and its precursors also showed a significant increase at this period. The results support that prodigiosin and/or its precursors are secondary metabolites. The ubiquity of the PCE activity in mutants deficient in prodigiosin biosynthesis suggest that this particular enzyme may also be present in non-pigmented clinical isolates.
灵菌红素缩合酶（PCE）活性存在于粘质沙雷氏菌野生型08、突变体OF、WF和9-3-3中。它们的比活性在细胞生长的对数后期或稳定期早期呈现出不同的最大值和不同的时间。在此期间，灵菌红素及其前体的水平也显著增加。结果支持灵菌红素和/或其前体是次生代谢产物。PCE活性在缺乏灵菌红素生物合成的突变体中普遍存在，这表明这种特殊的酶也可能存在于无色素的临床分离株中。
