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一种传统中药材(菊苣亚族)的完整叶绿体基因组。

The complete chloroplast genome of (Cichorioideae), a traditional Chinese medicinal plant.

作者信息

Li Peng, Fang Xiaoai, Liang Xiaoqing

机构信息

Department of Pharmacy, School of Medicine, Xi'an International University, Xi'an, China.

出版信息

Mitochondrial DNA B Resour. 2022 May 2;7(5):729-731. doi: 10.1080/23802359.2022.2068978. eCollection 2022.

Abstract

, Diels 1921 is a traditional Chinese medicinal plant of Cichorioideae, which contains many chemicals, such as friedelin, -sitosterol, stigmasterol, chlorogenic acid, and flavonoids, and so on, which has the characteristics of high medicinal value and small side effect. was used as folk medicines for anti-bacterial, and anti-oxidation, which also had a potential curative effect in preventing cardiovascular disease and anti-tumor. Illumina paired-end reads data were used to assemble the complete chloroplast (cp) genome. 14,425,796 raw paired-end reads and the length distribution in 124,685 bp, including a large single copy (LSC) region of 82,924 bp, a small single copy (SSC) region of 18,150 bp, and a pair of inverted repeat (IRs) regions of 25,128 bp. Besides, 10 protein-coding genes (PCGs) genes and 6 tRNAs genes possess a single intron, while and have a couple of introns. Based on the concatenated coding sequences of cp PCGs, the phylogenetic analysis showed that and (MH746729) are closely related to each other within the family Cichorioideae.

摘要

苦苣菜是菊苣亚科的一种传统中药材,它含有多种化学成分,如木栓酮、β-谷甾醇、豆甾醇、绿原酸和黄酮类化合物等,具有药用价值高、副作用小的特点。它曾被用作抗菌和抗氧化的民间药物,在预防心血管疾病和抗肿瘤方面也有潜在疗效。利用Illumina双端读取数据组装了完整的叶绿体(cp)基因组。共14,425,796条原始双端读取数据,长度分布在124,685bp,包括一个82,924bp的大单拷贝(LSC)区域、一个18,150bp的小单拷贝(SSC)区域和一对25,128bp的反向重复(IR)区域。此外,10个蛋白质编码基因(PCGs)和6个tRNA基因有一个内含子,而 和 有两个内含子。基于cp PCGs的串联编码序列的系统发育分析表明,苦苣菜和(MH746729)在菊苣亚科内彼此密切相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/51d2/9068008/9b624fa2ebc1/TMDN_A_2068978_F0001_B.jpg

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