Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, 730000, China.
Guangdong Provincial Key Laboratory of Plant Adaptation and Molecular Design, School of Life Sciences, Guangzhou University, Guangzhou, 510006, China.
J Integr Plant Biol. 2022 Jul;64(7):1303-1309. doi: 10.1111/jipb.13274. Epub 2022 Jun 9.
Receptor-like kinases (RLKs) are a large group of plant-specific transmembrane proteins mainly acting as receptors or co-receptors of various extracellular signals. They usually turn extracellular signals into intracellular responses via altering gene expression profiles. However, recent studies confirmed that many RLKs can physically interact with diverse membrane-localized transport proteins and regulate their activities for speedy responses in limited tissues or cells. In this minireview, we highlight recent discoveries regarding how RLKs can work with membrane transport proteins collaboratively and thereby trigger cellular responses in a precise and rapid manner. It is anticipated that such regulation broadly presents in plants and more examples will be gradually revealed when in-depth analyses are conducted for the functions of RLKs.
类受体激酶（RLKs）是一大类植物特有的跨膜蛋白，主要作为各种细胞外信号的受体或共受体。它们通常通过改变基因表达谱将细胞外信号转化为细胞内反应。然而，最近的研究证实，许多 RLKs 可以与各种膜定位的运输蛋白物理相互作用，并调节它们的活性，以便在有限的组织或细胞中快速响应。在这篇综述中，我们强调了最近关于 RLKs 如何与膜运输蛋白协同工作从而以精确和快速的方式触发细胞反应的发现。预计这种调节广泛存在于植物中，并且当对 RLKs 的功能进行深入分析时，将会逐渐揭示更多的例子。
