Clinical Microbiome Unit (CMU), Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Department of Biochemistry and Microbiology, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA.
Cell Host Microbe. 2022 May 11;30(5):607-611. doi: 10.1016/j.chom.2022.02.014.
Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the microbiome and normalize immune development to reduce the occurrence of C-section-associated inflammatory conditions. Here we discuss the rationale, evidence, and controversies surrounding such interventions.
母婴微生物播种干预措施使剖宫产（C -section）分娩的婴儿接触到他们在剖宫产过程中错过的母体微生物组。理论上，这些干预措施可以恢复微生物组并使免疫发育正常化，从而减少与 C -section 相关的炎症发生。在这里，我们讨论了这些干预措施的原理、证据和争议。
