文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

通过微流控纺丝制备的用于慢性伤口敷料的高吸水性海藻酸钙纤维支架。

High-water-absorbing calcium alginate fibrous scaffold fabricated by microfluidic spinning for use in chronic wound dressings.

作者信息

Cai Jie, Chen Xiaojing, Wang Xiaojing, Tan Yulu, Ye Dongdong, Jia Yongtang, Liu Peifeng, Yu Hui

机构信息

The Engineering Technology Research Center for Functional Textiles in Higher Education of Guangdong Province, College of Textile Materials and Engineering, Wuyi University Jiangmen 529020 China

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai 200032 China.

出版信息

RSC Adv. 2018 Nov 26;8(69):39463-39469. doi: 10.1039/c8ra06922k. eCollection 2018 Nov 23.

DOI:10.1039/c8ra06922k
PMID:35558052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9090719/
Abstract

More and more water-absorbing wound dressings have been studied since moist wound-healing treatment can effectively promote the healing of wounds. In this work, we introduce a novel method to produce improved wound dressings with high-water-absorbance. A high-water-absorbing calcium alginate (Ca-Alg) fibrous scaffold was fabricated simply by microfluidic spinning and centrifugal reprocessing. The structure and physical properties of the scaffold were characterized, and its water-absorbing, cytotoxicity properties and other applicability to wound dressings were comprehensively evaluated. Our results indicate that this material possesses high water-absorbing properties, is biocompatible, and has a 3D structure that mimics the extracellular matrix, while Ca-Alg fibers loaded with silver nanoparticles (AgNPs) exhibit broad-spectrum antibacterial activities; these properties meet the requirements for promoting the healing of chronic wounds and are widely applicable to wound dressings.

摘要

由于湿性伤口愈合疗法能够有效促进伤口愈合，越来越多的吸水性伤口敷料得到了研究。在这项工作中，我们介绍了一种生产具有高吸水性的改良伤口敷料的新方法。通过微流控纺丝和离心后处理简单地制备了一种高吸水性海藻酸钙（Ca-Alg）纤维支架。对该支架的结构和物理性能进行了表征，并对其吸水性、细胞毒性性能以及对伤口敷料的其他适用性进行了综合评估。我们的结果表明，这种材料具有高吸水性、生物相容性，并且具有模拟细胞外基质的三维结构，而负载银纳米颗粒（AgNPs）的Ca-Alg纤维表现出广谱抗菌活性；这些特性满足促进慢性伤口愈合的要求，并且广泛适用于伤口敷料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/928ff0af8aa4/c8ra06922k-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/b497c076279a/c8ra06922k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/428afabecf9c/c8ra06922k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/4801597a4526/c8ra06922k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/51121f7b3c40/c8ra06922k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/06a5bddb6996/c8ra06922k-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/d6dacf2e084a/c8ra06922k-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/700e76f15c2a/c8ra06922k-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/943152525bb2/c8ra06922k-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/928ff0af8aa4/c8ra06922k-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/b497c076279a/c8ra06922k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/428afabecf9c/c8ra06922k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/4801597a4526/c8ra06922k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/51121f7b3c40/c8ra06922k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/06a5bddb6996/c8ra06922k-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/d6dacf2e084a/c8ra06922k-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/700e76f15c2a/c8ra06922k-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/943152525bb2/c8ra06922k-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8479/9090719/928ff0af8aa4/c8ra06922k-f9.jpg

相似文献

[1]
High-water-absorbing calcium alginate fibrous scaffold fabricated by microfluidic spinning for use in chronic wound dressings.

RSC Adv. 2018-11-26

[2]
In situ reduction of silver nanoparticles by sodium alginate to obtain silver-loaded composite wound dressing with enhanced mechanical and antimicrobial property.

Int J Biol Macromol. 2020-1-17

[3]
Scar free healing of full thickness diabetic wounds: A unique combination of silver nanoparticles as antimicrobial agent, calcium alginate nanoparticles as hemostatic agent, fresh blood as nutrient/growth factor supplier and chitosan as base matrix.

Int J Biol Macromol. 2021-5-1

[4]
Improving anti-hemolytic, antibacterial and wound healing properties of alginate fibrous wound dressings by exchanging counter-cation for infected full-thickness skin wounds.

Mater Sci Eng C Mater Biol Appl. 2019-10-22

[5]
Modulation of NK cell activation by exogenous calcium from alginate dressings .

Front Immunol. 2023

[6]
Cobalt-mediated multi-functional dressings promote bacteria-infected wound healing.

Acta Biomater. 2018-12-30

[7]
Topical silver for infected wounds.

J Athl Train. 2009

[8]
Alginate membranes loaded with hyaluronic acid and silver nanoparticles to foster tissue healing and to control bacterial contamination of non-healing wounds.

J Mater Sci Mater Med. 2018-2-2

[9]
Microbial alginate dressings show improved binding capacity for pathophysiological factors in chronic wounds compared to commercial alginate dressings of marine origin.

J Biomater Appl. 2017-4

[10]
Alginate-Based Materials Loaded with Nanoparticles in Wound Healing.

Pharmaceutics. 2023-4-4

引用本文的文献

[1]
Advanced biomaterial strategies for overcoming age-associated wound healing impairments.

APL Bioeng. 2025-6-6

[2]
Functionalised Hybrid Collagen-Elastin for Acellular Cutaneous Substitute Applications.

Polymers (Basel). 2023-4-18

[3]
Alginate-Based Materials Loaded with Nanoparticles in Wound Healing.

Pharmaceutics. 2023-4-4

[4]
Alginate-Based Biomaterials in Tissue Engineering and Regenerative Medicine.

Mar Drugs. 2023-3-18

[5]
Calcium Alginate Production through Forward Osmosis with Reverse Solute Diffusion and Mechanism Analysis.

Membranes (Basel). 2023-2-8

[6]
Microfluidic Fabrication of Natural Polymer-Based Scaffolds for Tissue Engineering Applications: A Review.

Biomimetics (Basel). 2023-2-9

[7]
Different Curcumin-Loaded Delivery Systems for Wound Healing Applications: A Comprehensive Review.

Pharmaceutics. 2022-12-22

[8]
Graphene Oxide-alginate Hydrogel for Drawing Water through an Osmotic Membrane.

ACS Omega. 2022-10-18

[9]
Recent Progress in Development of Dressings Used for Diabetic Wounds with Special Emphasis on Scaffolds.

Biomed Res Int. 2022

[10]
Electrospun fibers and their application in drug controlled release, biological dressings, tissue repair, and enzyme immobilization.

RSC Adv. 2019-8-15

本文引用的文献

[1]
Designing electrospun nanofiber mats to promote wound healing - a review.

J Mater Chem B. 2013-9-28

[2]
Microfluidic spinning of the fibrous alginate scaffolds for modulation of the degradation profile.

Tissue Eng Regen Med. 2016-4-5

[3]
Large-scale water collection of bioinspired cavity-microfibers.

Nat Commun. 2017-10-20

[4]
Bioinspired Microfibers with Embedded Perfusable Helical Channels.

Adv Mater. 2017-6-22

[5]
Simultaneous microfluidic spinning of multiple strands of submicron fiber for the production of free-standing porous membranes for biological application.

Biofabrication. 2017-6-1

[6]
Terbinafine-loaded wound dressing for chronic superficial fungal infections.

Mater Sci Eng C Mater Biol Appl. 2017-4-1

[7]
Sodium alginate and gum acacia hydrogels of ZnO nanoparticles show wound healing effect on fibroblast cells.

Int J Biol Macromol. 2017-3

[8]
Electrospinning versus microfluidic spinning of functional fibers for biomedical applications.

Biomaterials. 2016-11-5

[9]
Simple Spinning of Heterogeneous Hollow Microfibers on Chip.

Adv Mater. 2016-5-17

[10]
Development and physicochemical characterization of alginate composite film loaded with simvastatin as a potential wound dressing.

Carbohydr Polym. 2015-11-2

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索