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电纺纤维及其在药物控释、生物敷料、组织修复和酶固定化中的应用。

Electrospun fibers and their application in drug controlled release, biological dressings, tissue repair, and enzyme immobilization.

作者信息

Sun Yue, Cheng Shihong, Lu Wenjuan, Wang Yanfeng, Zhang Pingping, Yao Qingqiang

机构信息

School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences Jinan 250062 Shandong China.

Institute of Materia Medica, Shandong Academy of Medical Sciences, Key Laboratory for Biotech-Drugs Ministry of Health, Key Laboratory for Rare & Uncommon Diseases of Shandong Province Jinan 250062 Shandong China

出版信息

RSC Adv. 2019 Aug 15;9(44):25712-25729. doi: 10.1039/c9ra05012d. eCollection 2019 Aug 13.

DOI:10.1039/c9ra05012d
PMID:35530076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9070372/
Abstract

Electrospinning is a method of preparing microfibers or nanofibers by using an electrostatic force to stretch the electrospinning fluid. Electrospinning has gained considerable attention in many fields due to its ability to produce continuous fibers from a variety of polymers and composites in a simple way. Electrospun nanofibers have many merits such as diverse chemical composition, easily adjustable structure, adjustable diameter, high surface area, high porosity, and good pore connectivity, which give them broad application prospects in the biomedical field. This review systematically introduced the factors influencing electrospinning, the types of electrospun fibers, the types of electrospinning, and the detailed applications of electrospun fibers in controlled drug release, biological dressings, tissue repair and enzyme immobilization fields. The latest progress of using electrospun fibers in these fields was summarized, and the main challenges to be solved in electrospinning technology were put forward.

摘要

静电纺丝是一种通过利用静电力拉伸静电纺丝液来制备微纤维或纳米纤维的方法。由于能够以简单的方式从多种聚合物和复合材料中生产连续纤维，静电纺丝在许多领域受到了广泛关注。静电纺纳米纤维具有许多优点，如化学成分多样、结构易于调节、直径可调节、表面积大、孔隙率高以及孔隙连通性好等，这些优点使其在生物医学领域具有广阔的应用前景。本文综述系统地介绍了影响静电纺丝的因素、静电纺纤维的类型、静电纺丝的类型，以及静电纺纤维在药物控释、生物敷料、组织修复和酶固定化领域的详细应用。总结了静电纺纤维在这些领域的最新进展，并提出了静电纺丝技术中有待解决的主要挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/f66dac298ed6/c9ra05012d-f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/d84b25f4c7e0/c9ra05012d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/09bc6563bf8e/c9ra05012d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/db8fdfe42636/c9ra05012d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/3c614346c30f/c9ra05012d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/5c1683725aba/c9ra05012d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/54f8ce4c464f/c9ra05012d-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/6cde554bb319/c9ra05012d-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/b00a80aeb5dc/c9ra05012d-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/376247412bf8/c9ra05012d-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/f66dac298ed6/c9ra05012d-f10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/d84b25f4c7e0/c9ra05012d-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/09bc6563bf8e/c9ra05012d-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/db8fdfe42636/c9ra05012d-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/3c614346c30f/c9ra05012d-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/5c1683725aba/c9ra05012d-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/54f8ce4c464f/c9ra05012d-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/6cde554bb319/c9ra05012d-f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/b00a80aeb5dc/c9ra05012d-f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/376247412bf8/c9ra05012d-f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78e/9070372/f66dac298ed6/c9ra05012d-f10.jpg

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本文引用的文献

[1]
High-water-absorbing calcium alginate fibrous scaffold fabricated by microfluidic spinning for use in chronic wound dressings.

RSC Adv. 2018-11-26

[2]
Incorporation of antimicrobial peptides on electrospun nanofibres for biomedical applications.

RSC Adv. 2018-8-6

[3]
Early stage release control of an anticancer drug by drug-polymer miscibility in a hydrophobic fiber-based drug delivery system.

RSC Adv. 2018-5-29

[4]
Preparation of poly(lactic acid)/graphene oxide nanofiber membranes with different structures by electrospinning for drug delivery.

RSC Adv. 2018-5-4

[5]
Novel SA@Ca/RCSPs core-shell structure nanofibers by electrospinning for wound dressings.

RSC Adv. 2018-4-24

[6]
Silver sulfadiazine loaded zein nanofiber mats as a novel wound dressing.

RSC Adv. 2019-1-2

[7]
Nanocellulose-based polymer hybrids and their emerging applications in biomedical engineering and water purification.

RSC Adv. 2019-6-18

[8]
Enhancement in sustained release of antimicrobial peptide and BMP-2 from degradable three dimensional-printed PLGA scaffold for bone regeneration.

RSC Adv. 2019-4-4

[9]
Enhancement of rotator cuff tendon-bone healing using combined aligned electrospun fibrous membranes and kartogenin.

RSC Adv. 2019-5-17

[10]
Electrospun organic-inorganic nanohybrids as sustained release drug delivery systems.

J Mater Chem B. 2017-12-14

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