• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

金纳米颗粒及金纳米颗粒标记抗体作为共反应物的电化学发光

Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants.

作者信息

Zhao Changzhi, Niu Lulu, Wang Xiaoyu, Sun Wei

机构信息

Key Laboratory of Sensor Analysis of Tumor Marker, The Ministry of Education, College of Chemistry & Molecular Engineering, Qingdao University of Science & Technology Qingdao 266042 China

Key Laboratory of Functional Materials and Photoelectronchemistry of Haikou, College of Chemistry and Chemical Engineering, Hainan Normal University Haikou 571158 China

出版信息

RSC Adv. 2018 Oct 24;8(63):36219-36222. doi: 10.1039/c8ra07429a. eCollection 2018 Oct 22.

DOI:10.1039/c8ra07429a
PMID:35558472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9092227/
Abstract

Gold nanoparticles (AuNPs) and AuNP-labelled antibodies can participate in the electrochemiluminescence (ECL) reaction of tris(2,2'-bipyridyl) ruthenium(ii) (Ru(bpy) ) as a co-reactant. The electrochemical and spectral characteristics of this new ECL system were confirmed by experiments, and its reaction mechanism was speculated to be different from that of typical ECL. The experimental results showed that the new ECL system exhibited higher ECL efficiency, and AuNP-labelled substances can be sensitively measured with the help of AuNPs. Based on the dual role of AuNPs as a co-reactant and marker, the AuNP-Ru(bpy) ECL system will be a useful tool in biochemical analysis.

摘要

金纳米颗粒（AuNPs）和AuNP标记的抗体可以作为共反应物参与三（2,2'-联吡啶）钌（II）（Ru(bpy) ）的电化学发光（ECL）反应。通过实验证实了这种新型ECL体系的电化学和光谱特性，并推测其反应机理与典型的ECL不同。实验结果表明，新型ECL体系具有更高的ECL效率，并且借助AuNPs可以灵敏地检测AuNP标记的物质。基于AuNPs作为共反应物和标记物的双重作用，AuNP-Ru(bpy) ECL体系将成为生化分析中的一种有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/e7ec3da90833/c8ra07429a-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/cb016119da11/c8ra07429a-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/b7f86ee4bf60/c8ra07429a-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/ec9cbc85d776/c8ra07429a-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/b2faf0370a12/c8ra07429a-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/e7ec3da90833/c8ra07429a-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/cb016119da11/c8ra07429a-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/b7f86ee4bf60/c8ra07429a-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/ec9cbc85d776/c8ra07429a-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/b2faf0370a12/c8ra07429a-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc4b/9092227/e7ec3da90833/c8ra07429a-f5.jpg

相似文献

1
Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants.金纳米颗粒及金纳米颗粒标记抗体作为共反应物的电化学发光
RSC Adv. 2018 Oct 24;8(63):36219-36222. doi: 10.1039/c8ra07429a. eCollection 2018 Oct 22.
2
Distance-dependent quenching and enhancing of electrochemiluminescence from tris(2, 2'-bipyridine) ruthenium (II)/tripropylamine system by gold nanoparticles and its sensing applications.金纳米粒子对三（2,2'-联吡啶）钌（II）/三丙胺体系电化学发光的距离相关猝灭和增强及其传感应用。
Biosens Bioelectron. 2018 Oct 30;118:80-87. doi: 10.1016/j.bios.2018.07.023. Epub 2018 Jul 26.
3
An "on-off-on" electrochemiluminescence aptasensor based on a self-enhanced luminophore for ochratoxin A detection.基于自增强发光体的“开-关-开”电化学发光适体传感器用于检测赭曲霉毒素 A。
Anal Bioanal Chem. 2023 Sep;415(23):5833-5844. doi: 10.1007/s00216-023-04864-8. Epub 2023 Jul 21.
4
Particle Size-Controlled Oxygen Reduction and Evolution Reaction Nanocatalysts Regulate Ru(bpy)'s Dual-potential Electrochemiluminescence for Sandwich Immunoassay.粒径可控的氧还原与析氧反应纳米催化剂调控Ru(bpy)的双电位电化学发光用于夹心免疫分析
Research (Wash D C). 2023 Apr 14;6:0117. doi: 10.34133/research.0117. eCollection 2023.
5
Novel cathodic electrochemiluminescence of tris(bipyridine) ruthenium(II) on a gold electrode in acidic solution.酸性溶液中金电极上三（2,2’-联吡啶）钌（II）的新型阴极电化学发光。
Analyst. 2012 Feb 7;137(3):588-94. doi: 10.1039/c1an15862g. Epub 2011 Dec 1.
6
A novel solid-state Ru(bpy)3(2+) electrochemiluminescence immunosensor based on poly(ethylenimine) and polyamidoamine dendrimers as co-reactants.基于聚乙烯亚胺和聚酰胺-胺树枝状大分子作为共反应物的新型固态 Ru(bpy)3(2+)电化学发光免疫传感器。
Talanta. 2015 Jan;131:192-7. doi: 10.1016/j.talanta.2014.07.072. Epub 2014 Aug 1.
7
Nanoscale-enhanced Ru(bpy)3(2+) electrochemiluminescence labels and related aptamer-based biosensing system.纳米级增强的钌（联吡啶）3（2+）电化学发光标记物及相关的基于适配体的生物传感系统。
Analyst. 2008 Sep;133(9):1209-13. doi: 10.1039/b806301j. Epub 2008 Jul 28.
8
Label-free Hg(II) electrochemiluminescence sensor based on silica nanoparticles doped with a self-enhanced Ru(bpy)-carbon nitride quantum dot luminophore.基于掺杂自增强 Ru(bpy)-碳氮量子点荧光体的硅纳米粒子的无标记 Hg(II)电化学发光传感器。
J Colloid Interface Sci. 2022 Feb 15;608(Pt 2):1151-1161. doi: 10.1016/j.jcis.2021.10.106. Epub 2021 Oct 21.
9
Tris(2,2'-bipyridyl)ruthenium (II) complex as a universal reagent for the fabrication of heterogeneous electrochemiluminescence platforms and its recent analytical applications.三联吡啶钌（II）配合物作为构建异质电化学发光平台的通用试剂及其近期的分析应用
Anal Bioanal Chem. 2023 Oct;415(24):5875-5898. doi: 10.1007/s00216-023-04876-4. Epub 2023 Jul 29.
10
Carboxyl groups on carbon nanodots as co-reactant sites for anodic electrochemiluminescence of tris(2,2-bipyridine)ruthenium(II).碳纳米点上的羧基作为三（2,2-联吡啶）钌（II）阳极电化学发光的共反应位点。
J Colloid Interface Sci. 2024 Jan;653(Pt B):1256-1263. doi: 10.1016/j.jcis.2023.09.122. Epub 2023 Sep 26.

引用本文的文献

1
Fabrication and characterization of glucose-oxidase-trehalase electrode based on nanomaterial-coated carbon paper.基于纳米材料包覆碳纸的葡萄糖氧化酶-海藻糖酶电极的制备与表征
RSC Adv. 2023 Nov 20;13(48):33918-33928. doi: 10.1039/d3ra01554h. eCollection 2023 Nov 16.

本文引用的文献

1
Role of Surface Hydrophobicity of Dicationic Amphiphile-Stabilized Gold Nanoparticles on A549 Lung Cancer Cells.双阳离子两亲分子稳定的金纳米颗粒的表面疏水性对A549肺癌细胞的作用
ACS Omega. 2017 Jul 31;2(7):3527-3538. doi: 10.1021/acsomega.7b00353. Epub 2017 Jul 25.
2
Recent biomedical applications of gold nanoparticles: A review.金纳米粒子在近期生物医学中的应用：综述。
Talanta. 2018 Jul 1;184:537-556. doi: 10.1016/j.talanta.2018.02.088. Epub 2018 Feb 26.
3
Applications of gold nanoparticles in virus detection.金纳米粒子在病毒检测中的应用。
Theranostics. 2018 Feb 15;8(7):1985-2017. doi: 10.7150/thno.23856. eCollection 2018.
4
Gold Nanoparticles as a Probe for Amyloid-β Oligomer and Amyloid Formation.金纳米颗粒作为淀粉样β寡聚体和淀粉样蛋白形成的探针
J Phys Chem C Nanomater Interfaces. 2017 Sep 14;121(36):20007-20015. doi: 10.1021/acs.jpcc.7b05169. Epub 2017 Aug 22.
5
Nanoparticle-Based Immunochemical Biosensors and Assays: Recent Advances and Challenges.基于纳米颗粒的免疫化学生物传感器和分析方法：最新进展和挑战。
Chem Rev. 2017 Aug 9;117(15):9973-10042. doi: 10.1021/acs.chemrev.7b00037. Epub 2017 Jul 28.
6
Recent Advances in Electrochemiluminescence Analysis.电化学发光分析的最新进展
Anal Chem. 2017 Jan 3;89(1):358-371. doi: 10.1021/acs.analchem.6b04675. Epub 2016 Dec 13.
7
Electrogenerated Chemiluminescence Resonance Energy Transfer between Ru(bpy)3(2+) Electrogenerated Chemiluminescence and Gold Nanoparticles/Graphene Oxide Nanocomposites with Graphene Oxide as Coreactant and Its Sensing Application.电致化学发光共振能量转移在 Ru(bpy)3(2+)电致化学发光和金纳米粒子/氧化石墨烯纳米复合材料之间的相互作用及其传感应用，其中氧化石墨烯作为共反应物。
Anal Chem. 2016 May 17;88(10):5469-75. doi: 10.1021/acs.analchem.6b00921. Epub 2016 Apr 29.
8
Fluorescence, Phosphorescence, and Chemiluminescence.荧光、磷光和化学发光。
Anal Chem. 2016 Jan 5;88(1):170-202. doi: 10.1021/acs.analchem.5b04109. Epub 2015 Dec 2.
9
General Strategy for Enhancing Electrochemiluminescence of Semiconductor Nanocrystals by Hydrogen Peroxide and Potassium Persulfate as Dual Coreactants.以过氧化氢和过硫酸钾作为双共反应剂增强半导体纳米晶体电化学发光的通用策略
Anal Chem. 2015 Dec 15;87(24):12372-9. doi: 10.1021/acs.analchem.5b03890. Epub 2015 Nov 24.
10
Quantum dots: electrochemiluminescent and photoelectrochemical bioanalysis.量子点：电化学发光与光电化学生物分析
Anal Chem. 2015 Oct 6;87(19):9520-31. doi: 10.1021/acs.analchem.5b00497. Epub 2015 Jun 19.