Orlewska Katarzyna, Kozieł Dorota, Klusek Justyna, Orlewska Ewa
Collegium Medicum, Jan Kochanowski University, 25-369 Kielce, Poland.
Int J Environ Res Public Health. 2022 Apr 29;19(9):5432. doi: 10.3390/ijerph19095432.
In 2020 COVID-19 caused 41,442 deaths in Poland. We aimed to estimate the burden of COVID-19 using years of potential life lost (YPLL) and quality-adjusted years of life lost (QALYL). YPLL were calculated by multiplying the number of deaths due to COVID-19 in the analyzed age/sex group by the residual life expectancy for that group. Standard and country-specific (local) life tables were used to calculate SPYLL and LPYLL, respectively. QALYL were calculated adjusting LPYLL due to COVID-19 death by age/sex specific utility values. Deaths from COVID-19 in Poland in 2020 caused loss of 630,027 SPYLL, 436,361 LPYLL, and 270,572 QALYL. The loss was greater among men and rose with age reaching the maximum among men aged 65-69 and among women aged 70-74. Burden of COVID-19 in terms of YPLL is proportionate to external-cause deaths and was higher than the burden of disease in the respiratory system. Differential effects by sex and age indicate important heterogeneities in the mortality effects of COVID-19 and justifies policies based not only on age, but also on sex. Comparison with YPLL due to other diseases showed that mortality from COVID-19 represents a substantial burden on both society and on individuals in Poland.
2020年，新型冠状病毒肺炎在波兰导致41442人死亡。我们旨在利用潜在寿命损失年数（YPLL）和质量调整生命年损失数（QALYL）来估算新型冠状病毒肺炎的负担。YPLL的计算方法是，将分析的年龄/性别组中因新型冠状病毒肺炎死亡的人数乘以该组的剩余预期寿命。分别使用标准生命表和特定国家（本地）生命表来计算标准化潜在寿命损失年数（SPYLL）和本地潜在寿命损失年数（LPYLL）。QALYL的计算方法是，根据年龄/性别特定效用值对因新型冠状病毒肺炎死亡导致的LPYLL进行调整。2020年波兰新型冠状病毒肺炎死亡导致630027个SPYLL、436361个LPYLL和270572个QALYL的损失。男性的损失更大，且随着年龄增长而上升，在65 - 69岁男性和70 - 74岁女性中达到最大值。就YPLL而言，新型冠状病毒肺炎的负担与外部原因导致的死亡成比例，且高于呼吸系统疾病的负担。性别和年龄的差异效应表明新型冠状病毒肺炎的死亡效应存在重要的异质性，这证明不仅基于年龄，而且基于性别的政策是合理的。与其他疾病导致的YPLL比较表明，新型冠状病毒肺炎的死亡率给波兰的社会和个人都带来了沉重负担。
