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外阴癌:2021年修订的国际妇产科联盟(FIGO)分期系统及影像学的作用

Vulvar Cancer: 2021 Revised FIGO Staging System and the Role of Imaging.

作者信息

Virarkar Mayur, Vulasala Sai Swarupa, Daoud Taher, Javadi Sanaz, Lall Chandana, Bhosale Priya

机构信息

Department of Diagnostic Radiology, University of Florida College of Medicine, 655 West 8th Street, C90, 2nd Floor, Clinical Center, Jacksonville, FL 32209, USA.

Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

出版信息

Cancers (Basel). 2022 Apr 30;14(9):2264. doi: 10.3390/cancers14092264.

DOI:10.3390/cancers14092264
PMID:35565394
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9102312/
Abstract

Vulvar cancer is a rare gynecological malignancy. It constitutes 5-8% of all gynecologic neoplasms, and squamous cell carcinoma is the most common variant. This article aims to review the etiopathogenesis revised 2021 International Federation of Gynecology and Obstetrics (FIGO) classification and emphasize imaging in the staging of vulvar cancer. The staging has been regulated by FIGO since 1969 and is subjected to multiple revisions. Previous 2009 FIGO classification is limited by the prognostic capability, which prompted the 2021 revisions and issue of a new FIGO classification. Although vulvar cancer can be visualized clinically, imaging plays a crucial role in the staging of the tumor, assessing the tumor extent, and planning the management. In addition, sentinel lymph node biopsy facilitates the histopathological staging of the draining lymph node, thus enabling early detection of tumor metastases and better survival rates.

摘要

外阴癌是一种罕见的妇科恶性肿瘤。它占所有妇科肿瘤的5 - 8%,其中鳞状细胞癌是最常见的类型。本文旨在回顾2021年国际妇产科联盟(FIGO)修订的病因发病机制分类,并强调外阴癌分期中的影像学检查。自1969年以来,FIGO一直在规范分期,并进行了多次修订。之前2009年的FIGO分类在预后能力方面存在局限性,这促使了2021年的修订并发布了新的FIGO分类。尽管外阴癌在临床上可以可视化,但影像学在外阴癌分期、评估肿瘤范围和制定治疗方案中起着至关重要的作用。此外,前哨淋巴结活检有助于对引流淋巴结进行组织病理学分期,从而能够早期发现肿瘤转移并提高生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d5/9102312/c781f60ba79b/cancers-14-02264-g011.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1d5/9102312/9b901abfa6f3/cancers-14-02264-g007.jpg
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2
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Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1(Suppl 1):7-18. doi: 10.1002/ijgo.13881.
3
Vulvar cancer staging: guidelines of the European Society of Urogenital Radiology (ESUR).外阴癌分期:欧洲泌尿生殖放射学会(ESUR)指南
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J Med Virol. 2025 Jul;97(7):e70459. doi: 10.1002/jmv.70459.
4
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6
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