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与无机牛骨(Bio-Oss)和富血小板血浆(PRP)相比,使用多孔氟羟基磷灰石(Algipore FRIOS)进行上颌窦底提升植入物的长期疗效:一项回顾性研究。

Long-Term Outcomes of Implants Placed in Maxillary Sinus Floor Augmentation with Porous Fluorohydroxyapatite (Algipore FRIOS) in Comparison with Anorganic Bovine Bone (Bio-Oss) and Platelet Rich Plasma (PRP): A Retrospective Study.

作者信息

Rapone Biagio, Inchingolo Alessio Danilo, Trasarti Stefano, Ferrara Elisabetta, Qorri Erda, Mancini Antonio, Montemurro Nicola, Scarano Antonio, Inchingolo Angelo Michele, Dipalma Gianna, Inchingolo Francesco

机构信息

Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.

Department of European Studies Jean Monnet of Lugano, 6900 Lugano, Switzerland.

出版信息

J Clin Med. 2022 Apr 28;11(9):2491. doi: 10.3390/jcm11092491.

Abstract

PURPOSE

The objective of this retrospective study was to evaluate the long-term clinical outcomes of bone regeneration procedures using algae-derived plant hydroxyapatite (Algipore FRIOS) compared with demineralized anorganic bovine bone (Bio-Oss), in combination with autologous blood-derived PRP.

MATERIALS AND METHODS

Partially edentulous patients with severe atrophy of posterior maxillary treated by means of the split bone technique in a two-stage grafting procedures were observed for up to seven years after implants placement. After surgeries, the natural porous fluorohydroxyapatite (FHA) (Algipore FRIOS; Group, = 29) or anorganic bovine bone (Bio-Oss Group, = 28) with autogenous bone in a 50:50 composite ratio with PRP, were administered in a 2.8-mm critical-size defect (CSD). Four months later, implants were placed at second-stage surgery.

RESULTS

A sample of fifty-seven consecutive patients who required sinus augmentation was included in the study, and 57 implants were placed. There was no drop out or loss of follow-up of any case. Clinical and radiographic examinations revealed a comparable pattern of newly formed bone in both groups after seven years of functional loading for implants placed after sinus augmentation using porous fluorohydroxyapatite and anorganic bovine bone. No significant difference in marginal bone loss was found around implants in both groups.

CONCLUSIONS

The favorable implant outcomes suggest both biomaterials are suitable for sinus grafting in severely atrophic maxillae.

摘要

目的

本回顾性研究的目的是评估使用藻类衍生的植物羟基磷灰石(Algipore FRIOS)与脱矿质无机牛骨(Bio-Oss)联合自体血源性富血小板血浆(PRP)进行骨再生手术的长期临床效果。

材料与方法

对采用劈开骨技术分两阶段进行植骨手术治疗的上颌后牙区严重萎缩的部分无牙患者,在植入种植体后观察长达七年。手术后,将天然多孔氟羟基磷灰石(FHA)(Algipore FRIOS组,n = 29)或无机牛骨(Bio-Oss组,n = 28)与自体骨以50:50的复合比例与PRP混合,植入2.8毫米的临界尺寸缺损(CSD)处。四个月后,在二期手术时植入种植体。

结果

本研究纳入了57例连续需要进行上颌窦提升的患者,并植入了57颗种植体。没有任何病例失访或随访丢失。临床和影像学检查显示,在使用多孔氟羟基磷灰石和无机牛骨进行上颌窦提升后植入种植体,经过七年的功能负载,两组新形成骨的模式具有可比性。两组种植体周围的边缘骨丢失没有显著差异。

结论

良好的种植体效果表明,这两种生物材料都适用于严重萎缩上颌骨的上颌窦植骨。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dd7/9105692/dc23f2f8ba88/jcm-11-02491-g001.jpg

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