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被戈登氏菌引起的起搏器心内膜炎。

Pacemaker-induced endocarditis by Gordonia bronchialis.

机构信息

Servicio de Microbiología, Hospital Universitario Miguel Servet Zaragoza, Spain.

Servicio de Microbiología, Hospital Universitario Miguel Servet Zaragoza, Spain.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2022 May;40(5):255-257. doi: 10.1016/j.eimce.2020.11.024.

DOI:10.1016/j.eimce.2020.11.024
PMID:35577444
Abstract

PURPOSE

Gordonia species are known to be opportunistic human pathogens causing secondary infections. We present the second case in the world of endocarditis caused by Gordonia bronchialis and a review of all the cases of endocarditis caused by Gordonia spp.

METHODS

The identification was performed by matrix-assisted desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing were performed to confirm the identification. Antimicrobial susceptibility was performed by MIC test Strip on Mueller-Hinton agar supplemented with 5% defibrinated sheep blood according to Clinical and Laboratory Standards Institute.

RESULTS

Pacemaker-induced endocarditis due to Gordonia bronchialis infection was determined in an 88-year old woman. The patient was treated with ceftriaxone and ciprofloxacin until completing 6 weeks from the pacemaker explant with a good evolution.

CONCLUSION

The case presented supports the pathogenic role of Gordonia bronchialis as an opportunistic pathogen and highlights the high risk of suffering infections caused by environmental bacteria.

摘要

目的

戈登氏菌属已知是机会性人类病原体,可引起继发性感染。我们报道了由支气管戈登氏菌引起的心内膜炎的世界第二例病例,并回顾了所有由戈登氏菌属引起的心内膜炎的病例。

方法

通过基质辅助解吸/电离飞行时间质谱(MALDI-TOF MS)进行鉴定,并通过 16S rRNA 基因测序进行确认。根据临床和实验室标准协会的规定,在含有 5%去纤维绵羊血的 Mueller-Hinton 琼脂上进行 MIC 试条法进行药敏试验。

结果

在一名 88 岁女性中确定了由支气管戈登氏菌感染引起的起搏器相关性心内膜炎。该患者接受头孢曲松和环丙沙星治疗,直至起搏器取出后 6 周,病情好转。

结论

所报告的病例支持支气管戈登氏菌作为机会性病原体的致病作用,并强调了因环境细菌而感染的高风险。

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