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加纳阿特瓦马-夸恩沃马地区孕妇用磺胺多辛-乙胺嘧啶间歇性预防治疗疟疾及其相关因素。

Intermittent Preventive Treatment of Malaria in Pregnancy with Sulphadoxine-Pyrimethamine and its Associated Factors in the Atwima Kwanwoma District, Ghana.

机构信息

Department of Health Administration and Education, Faculty of Science Education, University of Education, Winneba, Ghana.

Department of Public Health, Faculty of Health Sciences, Catholic University College of Ghana.

出版信息

Ann Glob Health. 2022 Apr 27;88(1):27. doi: 10.5334/aogh.3560. eCollection 2022.

Abstract

BACKGROUND

Intermittent preventive treatment of malaria in pregnancy with Sulphadoxine-Pyrimethamine (IPTp-SP) tablets is one of the recommended interventions to reduce the burden of malaria on both the pregnant woman and the unborn child. The aim of this study was to assess the prevalence of IPTp-SP uptake and its associated factors in the Atwima Kwanwoma District of Ashanti Region, Ghana.

METHODS

The study was cross sectional. A structured questionnaire was administered to 394 respondents, comprising pregnant women in their last two months of pregnancy and nursing mothers who delivered within three months prior to the study. Medical records of the respondents were also reviewed. Descriptive statistics such as simple proportions, and averages were computed. Chi-square test and multiple logistic regression analysis were performed to determine factors associated with IPTp-SP uptake.

RESULTS

The average age of the respondents was 28.2 (±5.9) years. Almost all of the respondents (98%) had received SP at the time of the study. Fifty percent received their first dose of SP between 16 and 19 weeks of gestation. The multiple logistic regression analysis showed a statistically significant association between IPTp-SP uptake and educational level, time of first ANC visit, number of ANC visits and receiving education on SP prior to the administration of the drug.

CONCLUSION

Education on SP use should be intensified at all levels of the health system. Early initiation of ANC is also recommended for optimal uptake of IPTp-SP. More research is needed to understand factors affecting the uptake of SP during pregnancy in the country.

摘要

背景

在妊娠期间间歇性预防疟疾治疗采用磺胺多辛-乙胺嘧啶(IPTp-SP)片剂是减少孕妇和胎儿疟疾负担的推荐干预措施之一。本研究旨在评估加纳阿散蒂地区阿特瓦马-夸恩沃马区的 IPTp-SP 接受率及其相关因素。

方法

本研究是横断面研究。对 394 名受访者(包括妊娠最后两个月的孕妇和在研究前三个月内分娩的哺乳期妇女)进行了结构化问卷调查,并查阅了受访者的病历。计算了简单比例和平均值等描述性统计数据。采用卡方检验和多因素逻辑回归分析来确定与 IPTp-SP 接受率相关的因素。

结果

受访者的平均年龄为 28.2(±5.9)岁。几乎所有受访者(98%)在研究时都接受了 SP。50%的人在妊娠 16-19 周时首次接受 SP 治疗。多因素逻辑回归分析显示,IPT-SP 接受率与教育程度、首次 ANC 就诊时间、ANC 就诊次数和在给药前接受 SP 教育呈统计学显著相关。

结论

应在卫生系统的各个层面加强 SP 使用教育。还建议早期启动 ANC,以优化 IPTp-SP 的接受率。需要更多的研究来了解影响该国孕妇 SP 接受率的因素。

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