Stuss D T, Kates M H, Poirier C A, Hylton D, Humphreys P, Keene D, Laflèche G
J Clin Exp Neuropsychol. 1987 Apr;9(2):131-46. doi: 10.1080/01688638708405353.
Patients with myotonic dystrophy (MD) were compared to a control group, matched to the patients in important demographic variables including IQ, on the Sternberg Memory Scanning procedure, to investigate the hypothesis of a selective change in speed of information processing in MD patients. The neuropsychological functioning of these MD patients was also compared to normative data to provide a descriptive picture of their abilities; these results were correlated to the factors of age of onset and duration of the disease. Finally, the MD patients were also compared to the defined control group on the neuropsychological measures. There was little evidence of selective slowness of information processing or particular deficit independent of overall IQ. Neuropsychologically, the MD patients as a group performed at the low average level. There was, however, a wide range of abilities, suggesting that MD patients are not a unitary group in terms of neuropsychological functioning. Age of onset of the disease was important, at least for certain results. Further research of the neuropsychological functioning of MD patients must account for the wide range of results, with more precise measures of actual onset of the disease and muscular weakness, in a longitudinal evaluation.
将患有强直性肌营养不良（MD）的患者与一个对照组进行比较，该对照组在包括智商在内的重要人口统计学变量上与患者相匹配，采用斯滕伯格记忆扫描程序，以研究MD患者信息处理速度存在选择性变化的假设。还将这些MD患者的神经心理功能与常模数据进行比较，以描绘他们能力的概况；这些结果与发病年龄和病程因素相关。最后，在神经心理学测量方面，也将MD患者与明确的对照组进行比较。几乎没有证据表明存在信息处理的选择性迟缓或独立于整体智商的特定缺陷。从神经心理学角度来看，MD患者作为一个群体的表现处于低平均水平。然而，能力范围很广，这表明MD患者在神经心理功能方面并非一个单一的群体。疾病的发病年龄很重要，至少对于某些结果是这样。对MD患者神经心理功能的进一步研究必须考虑到结果的广泛差异，在纵向评估中更精确地测量疾病和肌肉无力的实际发病情况。
