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瑞典西哥特兰地区铁路附近居民的铁路噪声与糖尿病:肥胖指标的横断面中介分析。

Railway noise and diabetes among residents living close to the railways in Västra Götaland, Sweden: Cross-sectional mediation analysis on obesity indicators.

机构信息

Sound Environment and Health, Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Sound Environment and Health, Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

出版信息

Environ Res. 2022 Sep;212(Pt B):113477. doi: 10.1016/j.envres.2022.113477. Epub 2022 May 16.

DOI:10.1016/j.envres.2022.113477
PMID:35588775
Abstract

Railway noise is expected to increase in Europe and Sweden as well, following recommendations for a more sustainable transportation mode. This forecasted increase might lead to higher level of noise exposure, higher population exposure and potentially increased night-time exposure. Evidence supports an effect of transportation noise on several health outcomes, including metabolic conditions such as diabetes. However, few studies were directed to railway noise; present studies on railway noise and diabetes so far show ambiguous results while some studies report an association between railway noise and obesity. The aim of this study is to investigate the relationship between railway noise and diabetes prevalence and to assess whether obesity might be a mediator in this association. The study population (N = 5381) was randomly selected from residents living within 1 km of a trafficked railway in Västra Götaland, Sweden. Survey data was combined with modelled exposures and health register data (ICD10 codes for diabetes). The study uses a cross sectional design, logistic regression analysis and a counterfactual mediation analysis. We found an increase in the prevalence of diabetes associated with the exposure to railway noise: OR = 1.33 per 10 dB increase L (95% CI 1.09-1.63) accounting for sociodemographic and lifestyle factors. BMI and waist circumference partially mediate the association between railway noise and diabetes. This is the first study to report an association between railway noise and diabetes in Sweden. BMI and waist circumference seem to be a potential mediators in this association. Still, future studies should further explore the mechanisms from noise to diabetes, considering different pathways in relation to obesity but also exploring other potential mediators.

摘要

随着对更可持续交通方式的建议,欧洲和瑞典的铁路噪音预计也会增加。这种预测的增加可能会导致噪声暴露水平更高、更多的人群暴露和潜在的夜间暴露增加。有证据表明,交通噪声对包括糖尿病在内的几种健康结果有影响。然而,很少有研究针对铁路噪声;目前关于铁路噪声和糖尿病的研究结果尚不清楚,而一些研究报告称铁路噪声与肥胖之间存在关联。本研究旨在调查铁路噪声与糖尿病患病率之间的关系,并评估肥胖是否可能是这种关联的中介因素。研究人群(N=5381)是从瑞典西约塔兰地区居住在交通繁忙铁路 1 公里范围内的居民中随机选择的。调查数据与模型暴露和健康登记数据(糖尿病 ICD10 代码)相结合。该研究采用横断面设计、逻辑回归分析和反事实中介分析。我们发现,与接触铁路噪声相关的糖尿病患病率增加:OR=1.33/10dB 增加 L(95%CI 1.09-1.63),这与社会人口统计学和生活方式因素有关。BMI 和腰围部分介导了铁路噪声与糖尿病之间的关联。这是首次在瑞典报告铁路噪声与糖尿病之间存在关联的研究。BMI 和腰围似乎是这种关联的潜在中介因素。尽管如此,未来的研究仍应进一步探讨噪声与糖尿病之间的机制,考虑与肥胖有关的不同途径,同时还应探索其他潜在的中介因素。

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