Zhang Yanfeng, Wang Rui, Hua Yuyan, Baumgartner Ryan, Cheng Jianjun
Department of Materials Science and Engineering and ‡Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Department of Materials Science and Engineering and Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
ACS Macro Lett. 2014 Jul 15;3(7):693-697. doi: 10.1021/mz500277j. Epub 2014 Jul 3.
Water-soluble, acrylate-terminated poly(β-amino esters) with built-in trigger-responsive domains were synthesized through Michael addition of trigger-responsive diacrylates and primary amines. They were used as macromolecular precursors for photoinitiated cross-linking reactions to prepare trigger-responsive hydrogels for protein encapsulation. The encapsulated proteins could be rapidly released upon external triggering.
通过触发响应性二丙烯酸酯与伯胺的迈克尔加成反应，合成了具有内置触发响应域的水溶性丙烯酸酯封端的聚（β-氨基酯）。它们被用作光引发交联反应的大分子前体，以制备用于蛋白质包封的触发响应水凝胶。包封的蛋白质在外部触发时可以快速释放。
