Onaciu Anca, Munteanu Raluca Andrada, Moldovan Alin Iulian, Moldovan Cristian Silviu, Berindan-Neagoe Ioana
Medfuture-Research Center for Advanced Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, Marinescu 23/Pasteur 4-6 Street, 400337 Cluj-Napoca, Romania.
Department of Pharmaceutical Physics-Biophysics, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, Pasteur 6 Street, 400349 Cluj-Napoca, Romania.
Pharmaceutics. 2019 Aug 23;11(9):432. doi: 10.3390/pharmaceutics11090432.
Hydrogels represent 3D polymeric networks specially designed for various medical applications. Due to their porous structure, they are able to swollen and to entrap large amounts of therapeutic agents and other molecules. In addition, their biocompatibility and biodegradability properties, together with a controlled release profile, make hydrogels a potential drug delivery system. In vivo studies have demonstrated their effectiveness as curing platforms for various diseases and affections. In addition, the results of the clinical trials are very encouraging and promising for the use of hydrogels as future target therapy strategies.
水凝胶是专门为各种医学应用设计的三维聚合物网络。由于其多孔结构，它们能够膨胀并捕获大量治疗剂和其他分子。此外，它们的生物相容性和生物降解性，以及可控的释放特性，使水凝胶成为一种潜在的药物递送系统。体内研究已经证明它们作为各种疾病和病症的治疗平台的有效性。此外，临床试验结果对于将水凝胶用作未来的靶向治疗策略非常令人鼓舞且前景广阔。
