Kikuchi Daisuke, Odagiri Hiroyuki, Hoshihara Yoshio, Ochiai Yorinari, Suzuki Yugo, Hayasaka Junnosuke, Tanaka Masami, Nomura Kosuke, Yamashita Satoshi, Matsui Akira, Iizuka Toshiro, Hoteya Shu
Department of Gastroenterology, Toranomon Hospital, Japan.
Gastroenterol Res Pract. 2022 May 13;2022:3952962. doi: 10.1155/2022/3952962. eCollection 2022.
Gastroesophageal reflux disease is diagnosed endoscopically based on the presence of mucosal breaks. However, mucosal breaks can be judged differently depending on the endoscopist, even in the same image. We investigated how narrow-band imaging (NBI) and magnified endoscopy affect the judgment of mucosal breaks.
A total of 43 consecutive patients were enrolled who had suspected mucosal breaks on white-light images (WLI) and underwent nonmagnified NBI (N-NBI) and magnified NBI (M-NBI) by a single endoscopist. From WLI, N-NBI, and M-NBI, 129 image files were created. Eight endoscopists reviewed the image files and judged the presence of mucosal breaks.
The 8 endoscopists determined mucosal breaks were present in 79.4 ± 9.5% (67.4%-93.0%) on WLI, and 76.7 ± 12.7% (53.5%-90.7%) on N-NBI. However, the percentage of mucosal breaks on M-NBI was significantly lower at 48.8 ± 17.0% (18.6%-65.1%) ( < 0.05). Intraclass correlation between observers was 0.864 (95% CI 0.793-0.918) for WLI and 0.863 (95% CI 0.791-0.917) for N-NBI but was lower for M-NBI at 0.758 (95% CI 0.631-0.854).
Rates of detection and agreement for mucosal breaks on WLI and N-NBI were high among endoscopists. However, these rates were lower on M-NBI.
胃食管反流病通过内镜检查根据黏膜破损的存在来诊断。然而,即使在同一图像中,不同内镜医师对黏膜破损的判断也可能不同。我们研究了窄带成像(NBI)和放大内镜检查如何影响对黏膜破损的判断。
连续纳入43例白光图像(WLI)上疑似有黏膜破损的患者,由一名内镜医师对其进行非放大NBI(N-NBI)和放大NBI(M-NBI)检查。从WLI、N-NBI和M-NBI中创建了129个图像文件。8名内镜医师对这些图像文件进行审查并判断是否存在黏膜破损。
8名内镜医师判定WLI上黏膜破损的比例为79.4±9.5%(67.4%-93.),N-NBI上为76.7±12.7%(53.5%-90.7%)。然而,M-NBI上黏膜破损的比例显著较低,为48.8±17.0%(18.6%-65.1%)(P<0.05)。观察者之间的组内相关性,WLI为0.864(95%CI 0.793-0.918),N-NBI为0.863(95%CI 0.791-0.917),但M-NBI较低,为0.758(95%CI 0.631-0.854)。
内镜医师对WLI和N-NBI上黏膜破损的检出率和一致性较高。然而,M-NBI上的这些率较低。