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[暴露于加速碳离子的大鼠大脑皮质神经元形态学变化的发生率]

[Incidence of morphologic changes in cerebral cortex neurons of the rat exposed to accelerated carbon ions].

作者信息

Fedorenko B S, Kabitsyna R A, Krivitskaia G N, Dereviagin V I, Ryzhov N I

出版信息

Kosm Biol Aviakosm Med. 1987 Jan-Feb;21(1):51-5.

PMID:3560848
Abstract

Structural lesions in neurons of the brain cortex of rats were investigated 1 and 3 months after their exposure to accelerated carbon ions with the energy 320 MeV/nuclon 10(4) particles/cm2 (LET = 120 MeVcm2/g) as well as to gamma-radiation in the dose 1.0 Gy. The irradiated animals showed morphofunctional, dystrophic and reparative lesions in neurons. The rats exposed to carbon ions developed more distinct changes that the animals exposed to gamma-radiation. It is postulated that similar fluxes of cosmic radiations will not produce a deleterious effect on the integrative functions of the central nervous system of cosmonauts.

摘要

在大鼠暴露于能量为320兆电子伏特/核子、剂量为10⁴粒子/平方厘米(传能线密度LET = 120兆电子伏特·平方厘米/克)的加速碳离子以及剂量为1.0戈瑞的γ射线辐射后1个月和3个月,对其大脑皮质神经元的结构损伤进行了研究。受辐照的动物神经元出现了形态功能、营养不良和修复性损伤。暴露于碳离子的大鼠所发生的变化比暴露于γ射线辐射的动物更为明显。据推测,类似的宇宙辐射通量不会对宇航员中枢神经系统的整合功能产生有害影响。

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