Broderick J P, Sandok B A, Mertz L E
Mayo Clin Proc. 1987 Apr;62(4):313-6. doi: 10.1016/s0025-6196(12)61910-7.
A 19-year-old woman had severe focal inflammatory encephalitis. Six years previously, she had had classic untreated Lyme disease characterized by erythema chronicum migrans, bilateral facial palsies, and lymphocytic meningitis. During her recent encephalitic illness, Lyme disease serologic tests were positive by indirect immunofluorescence microscopy, enzyme-linked immunosorbent assay, and western blot (immunoblot technique) testing. We hypothesize that the patient's focal inflammatory encephalitis was a result of a persistent spirochetal infection of the central nervous system.
一名19岁女性患有严重的局灶性炎性脑炎。六年前,她患过未经治疗的典型莱姆病,其特征为慢性游走性红斑、双侧面神经麻痹和淋巴细胞性脑膜炎。在她最近的脑炎疾病期间,通过间接免疫荧光显微镜检查、酶联免疫吸附测定和蛋白质印迹(免疫印迹技术)检测,莱姆病血清学检测呈阳性。我们推测该患者的局灶性炎性脑炎是中枢神经系统持续性螺旋体感染的结果。