UOC Ginecologia Oncologica, Dipartimento per la salute della Donna e del Bambino e della Salute Pubblica, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Department of Surgical Oncology, Institut Claudius Regaud, Institut Universitaire du Cancer de Toulouse Oncopole (IUCT-Oncopole), Toulouse, France.
Ann Surg Oncol. 2022 Sep;29(9):5906-5907. doi: 10.1245/s10434-022-11870-0. Epub 2022 May 24.
Preservation of ovarian function is important for the physical and psychosexual well-being of young patients with cancer. Patients with pelvic malignancies such as cervical or rectal cancer planned for radiotherapy may benefit from ovarian transposition with the aim of moving the ovaries outside the radiation field. Different surgical techniques have been reported previously. With the present video, we aim to standardize the surgical technique of laparoscopic ovarian transposition in ten steps. We present the case of a 30-year-old nulliparous woman diagnosed with grade 3 squamous cell cervical carcinoma having a largest tumor diameter of 41 mm on magnetic resonance imaging (MRI) scan. The tumor was staged as FIGO 2018 stage IIIC1r with a common iliac lymphadenopathy reported on both MRI and positron emission tomography (PET)/computed tomography (CT) scan. The multidisciplinary team recommended exclusive chemoradiation extended to paraaortic area. The patient underwent laparoscopic bilateral salpingectomy and bilateral ovarian transposition with extraperitonealization of the infundibulopelvic ligament. The procedure was divided into the following ten steps: division of uteroovarian ligament, incision of lateral pelvic peritoneum, identification of ureter, incision of medial pelvic peritoneum, skeletonization of the infundibulopelvic ligament, retroperitoneal tunnel in paracolic gutter, creating the window (as high as possible), mobilization of the ovary without torsion, intraperitonealization of the ovary, and fix ovary with clips (Fig. 1). Surgical time was 30 min, with minimal estimated blood loss. No intra- or postoperative complication was recorded. The patient started radiotherapy 14 days after the procedure. In conclusion, we showed that laparoscopic ovarian transposition in cervical cancer before radiotherapy can be standardized in ten steps with encouraging perioperative results, making it an easily reproducible procedure. Ovarian function is reported to be preserved in 62-65% of cases undergoing ovarian transposition and radiation therapy. Fig. 1 Laparoscopic view of right ovary transposed below the liver edge after extraperitonealization of the infudibulopelvic ligament.
保留卵巢功能对于患有癌症的年轻患者的身体和心理性健康至关重要。计划接受放疗的盆腔恶性肿瘤(如宫颈癌或直肠癌)患者可能受益于卵巢移位,目的是将卵巢移出放射野。此前已经报道了不同的手术技术。通过本视频,我们旨在以十个步骤标准化腹腔镜卵巢移位的手术技术。我们介绍了一位 30 岁的未育妇女的病例,她被诊断患有 3 级宫颈鳞状细胞癌,磁共振成像(MRI)扫描显示最大肿瘤直径为 41mm。肿瘤分期为 2018 年 FIGO ⅡIC1r 期,MRI 和正电子发射断层扫描(PET)/计算机断层扫描(CT)均报告有髂淋巴结肿大。多学科团队建议进行单纯放化疗,扩展至腹主动脉旁区域。该患者接受了腹腔镜双侧输卵管切除术和双侧卵巢移位术,并将输卵管卵巢韧带进行了腹膜外化。该手术过程分为以下十个步骤:子宫卵巢韧带的分离、侧盆腹膜的切开、输尿管的识别、盆腹膜的切开、输卵管卵巢韧带的骨骼化、结肠旁沟的腹膜后隧道、创建窗口(尽可能高)、卵巢的无扭转移动、卵巢的腹膜内化和用夹固定卵巢(图 1)。手术时间为 30 分钟,估计出血量最小。未记录到术中或术后并发症。患者在手术后 14 天开始接受放疗。总之,我们表明,在宫颈癌放疗前进行腹腔镜卵巢移位可以通过十个步骤标准化,具有令人鼓舞的围手术期结果,使其成为一种易于复制的手术。卵巢移位和放疗后,卵巢功能被报告保留在 62-65%的病例中。图 1 右侧卵巢经输卵管卵巢韧带腹膜外化后置于肝缘下方的腹腔镜视图。