Department of Obstetrics and Gynecology, Chongqing Health Center for Women and Children, Chongqing 401147, Chongqing, China.
Department of Gynecological Endocrinology, Chongqing Health Center for Women and Children, Chongqing 401147, Chongqing, China.
Comput Intell Neurosci. 2022 May 16;2022:6154233. doi: 10.1155/2022/6154233. eCollection 2022.
Polycystic ovary syndrome (PCOS) is now a common gynecological endocrine disease, also known as Stein-Leventhal syndrome. Studies have found that Vaspin gene polymorphism is significantly associated with diabetes and cardiovascular disease, and PCOS has a clear glucose metabolism abnormality. So far, because the cause of PCOS is not clear, many problems such as the etiology, diagnostic criteria, prevention, and treatment of PCOS remain unsolved. Which also makes PCOS attract the attention of academic circles. Therefore, it is urgent to clarify the pathogenesis of PCOS, in order to explore the clinical correlation between the polymorphism of the Vaspin gene and polycystic ovary syndrome. This article introduces the correlation analysis study of Vaspin gene polymorphisms and polycystic ovary syndrome based on intelligent medicine. This article first selected 40 patients with PCOS as the experimental group and then selected 40 patients without PCOS as the control group. Secondly, through the detection methods of hs-CRP level detection and oil red O fat staining and passed two sets of control experiments. Finally, intelligent medical data analysis was used to analyze the location of the Vaspin gene in the experimental group and the control group. The final result showed that the correlation reached 75%.
多囊卵巢综合征（PCOS）现为常见的妇科内分泌疾病，又称 Stein-Leventhal 综合征。研究发现，Vaspin 基因多态性与糖尿病和心血管疾病明显相关，而 PCOS 存在明显的糖代谢异常。迄今为止，由于 PCOS 的病因尚不明确，其病因、诊断标准、预防和治疗等诸多问题仍未解决。这也使得 PCOS 备受学术界关注。因此，迫切需要阐明 PCOS 的发病机制，以便探讨 Vaspin 基因多态性与多囊卵巢综合征的临床相关性。本文基于智能医学介绍了 Vaspin 基因多态性与多囊卵巢综合征的相关性分析研究。本文首先选择 40 例 PCOS 患者作为实验组，然后选择 40 例非 PCOS 患者作为对照组。其次，通过 hs-CRP 水平检测和油红 O 脂肪染色的检测方法进行了两组对照实验。最后，采用智能医学数据分析方法分析了实验组和对照组中 Vaspin 基因的位置。最终结果显示相关性达到 75%。
