9型旋转分泌系统的设计原理

Trivedi Abhishek, Gosai Jitendrapuri, Nakane Daisuke, Shrivastava Abhishek

School of Life Sciences, Arizona State University, Tempe, AZ, United States.

Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.

Front Microbiol. 2022 May 10;13:845563. doi: 10.3389/fmicb.2022.845563. eCollection 2022.

The F ATP synthase, the bacterial flagellar motor, and the bacterial type 9 secretion system (T9SS) are the three known proton motive force driven biological rotary motors. In this review, we summarize the current information on the nuts and bolts of T9SS. Torque generation by T9SS, its role in gliding motility of bacteria, and the mechanism which a T9SS-driven swarm shapes the microbiota are discussed. The knowledge gaps in our current understanding of the T9SS machinery are outlined.

F型ATP合酶、细菌鞭毛马达和细菌9型分泌系统（T9SS）是已知的三种由质子动力驱动的生物旋转马达。在本综述中，我们总结了目前关于T9SS基本组成部分的信息。讨论了T9SS产生扭矩的机制、其在细菌滑行运动中的作用以及T9SS驱动的群体塑造微生物群的机制。概述了我们目前对T9SS机制理解中的知识空白。