Martínez-Noguera Francisco Javier, Alcaraz Pedro E, Carlos-Vivas Jorge, Marín-Pagán Cristian
Research Center for High Performance Sport, Catholic University of Murcia (UCAM), Campus de los Jerónimos Nº 135, 30107 Murcia, Spain.
Health, Economy, Motricity and Education Research Group (HEME), Faculty of Sport Sciences, University of Extremadura, Avda. de Elvas, s/n., 06006 Badajoz, Spain.
Biology (Basel). 2022 May 11;11(5):736. doi: 10.3390/biology11050736.
Chronic supplementation with 2S-hesperidin improves performance; however, the mechanisms underlying this effect have not yet been explored. Therefore, the aim of this study was to assess whether changes in acid-base status may be associated with improved performance after 2S-hesperidin supplementation compared to microcellulose (placebo). Forty amateur cyclists (n = 20 per group) underwent a rectangular test where capillary blood samples were taken at baseline, FatMax1, VT1, VT2, P, FatMax2 and EPOC to measure acid-base parameters. After eight weeks of 2S-hesperidin supplementation (500 mg/d) increased HCO, SBC, ABE ( ≤ 0.05) and decreased Lac were found at FatMax1, VT1, FatMax2 and EPOC ( ≤ 0.05), while decreased Lac at VT2 was found with a large effect size (ES = 1.15) compared to placebo. Significant group differences in the area under the curve were observed when comparing pre-post-intervention pH changes ( = 0.02) between groups. Chronic supplementation with 2S-hesperidin improved acid-base status and Lac, both at low-moderate and submaximal intensities, improving recovery after exercise-to-exhaustion in amateur cyclists.
长期补充2S-橙皮苷可提高运动表现；然而，这种作用的潜在机制尚未得到探索。因此，本研究的目的是评估与微晶纤维素（安慰剂）相比，补充2S-橙皮苷后酸碱状态的变化是否可能与运动表现的改善有关。40名业余自行车运动员（每组n = 20）进行了一项矩形测试，在基线、脂肪代谢峰值1、第一通气阈值、第二通气阈值、峰值功率、脂肪代谢峰值2和运动后过量氧耗时采集毛细血管血样，以测量酸碱参数。在补充2S-橙皮苷（500 mg/d）八周后，在脂肪代谢峰值1、第一通气阈值、脂肪代谢峰值2和运动后过量氧耗时发现碳酸氢根、标准碳酸氢盐、碱剩余增加（P≤0.05），乳酸降低（P≤0.05），而与安慰剂相比，在第二通气阈值时乳酸降低且效应量较大（ES = 1.15）。在比较组间干预前后pH变化的曲线下面积时，观察到显著的组间差异（P = 0.02）。长期补充2S-橙皮苷可改善低中强度和次最大强度下的酸碱状态和乳酸水平，提高业余自行车运动员运动至疲劳后的恢复能力。
