Messinis Lambros, Nasios Grigorios, Mougias Antonios, Patrikelis Panayiotis, Malefaki Sonia, Panagiotopoulos Vasileios, Ntoskou Messini Aikaterini, Bakirtzis Christos, Grigoriadis Nikolaos, Ioannidis Panagiotis, Bairami Stella, Papadopoulou Valentina, Gourzis Phillipos
School of Psychology, Laboratory of Cognitive Neuroscience, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Department of Psychiatry, University of Patras Medical School, 265 00 Patras, Greece.
Healthcare (Basel). 2022 May 13;10(5):906. doi: 10.3390/healthcare10050906.
: Cognitive screening instruments (CSIs) are essential for everyday practice. The Quick Mild Cognitive Impairment (Qmci) screen, a short instrument designed to identify mild cognitive impairment, was recently translated into Greek (Qmci-Gr). The present study compared its diagnostic value against the Montreal Cognitive Assessment (MoCA) screen and examined its optimal cutoffs. : We recruited consecutive patients aged ≥55 years that presented with cognitive complaints from two outpatient clinics in Greece. The Q-Gr and MoCA were completed by all patients. Furthermore, they were assessed independently with a comprehensive flexible neuropsychological battery to establish a diagnostic classification. : In the current study, we assessed a total of 145 patients, with a median age of 70 years; 44 were classified as having Subjective Memory Complaints (SMC) but normal cognition, 32 with MCI and 69 with dementia. The Qmci-Gr had a higher accuracy compared to the MoCA in discriminating MCI from dementia, area under the curve (AUC) of 0.81 versus 0.75, respectively; however, this finding was marginally significant ( = 0.08). Its accuracy was marginally higher for distinguishing SMC from dementia, AUC of 0.94 versus 0.89 ( = 0.03). However, Qmci-Gr presented a lower accuracy than MoCa in differentiating SMC from MCI, AUC of 0.76 versus 0.94 ( = 0.006). : The Qmci-Gr has comparable diagnostic accuracy to the MoCA regarding MCI and dementia groups. Further research, with larger and more diverse samples, may be necessary to ensure generalizability.
认知筛查工具（CSIs）在日常医疗实践中至关重要。快速轻度认知障碍（Qmci）筛查是一种用于识别轻度认知障碍的简短工具，最近已被翻译成希腊语（Qmci-Gr）。本研究将其诊断价值与蒙特利尔认知评估（MoCA）筛查进行了比较，并检查了其最佳临界值。我们从希腊的两家门诊诊所招募了年龄≥55岁且有认知主诉的连续患者。所有患者均完成了Q-Gr和MoCA测试。此外，他们还接受了全面灵活的神经心理成套测验的独立评估，以确定诊断分类。在本研究中，我们共评估了145名患者，中位年龄为70岁；44名被归类为有主观记忆主诉（SMC）但认知正常，32名患有轻度认知障碍（MCI），69名患有痴呆症。在区分MCI和痴呆症方面，Qmci-Gr的准确性高于MoCA，曲线下面积（AUC）分别为0.81和0.75；然而，这一发现仅具有边缘显著性（P = 0.08）。在区分SMC和痴呆症方面，其准确性略高，AUC分别为0.94和0.89（P = 0.03）。然而，在区分SMC和MCI方面，Qmci-Gr的准确性低于MoCa，AUC分别为0.76和0.94（P = 0.006）。Qmci-Gr在MCI和痴呆症组方面具有与MoCA相当的诊断准确性。可能需要进行更大规模、更多样化样本的进一步研究，以确保结果具有普遍性。
