Discipline of Psychiatry, Department of Clinical Sciences, "George Emil Palade" University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Str. G. Marinescu, 540139 Targu Mures, Romania.
Mental Health Center No. 1, "Pius Branzeu" Timis County Emergency Clinical Hospital, 156 Bd. Liviu Rebreanu, 300182 Timisoara, Romania.
Medicina (Kaunas). 2022 Apr 28;58(5):615. doi: 10.3390/medicina58050615.
: Current psychiatric care is increasingly focusing on patients' quality of life (QoL). Research is still trying to determine the main factors which influence QoL. The present study aims to assess the QoL of patients with chronic psychotic-spectrum disorders, as well as its relation to symptomatology, functionality, adaptive behavior, and perceived level of recovery. : The study included a sample of 78 patients with chronic psychosis. Symptomatology and illness severity were assessed with the Positive and Negative Syndrome Scale (PANSS) and the Clinical Global Impression Scale-Severity (CGI-S) scales, respectively. The Global Assessment of Functioning Scale (GAFS) and the Adaptive Behavior Assessment System II (ABAS-II)-Adult Form were used for the assessment of patients' functionality, and the Quality-of-Life Inventory (QOLI) scale was applied for the evaluation of QoL. : According to the CGI-Severity scale, 20.5% of the patients were borderline mentally ill, and 24.4% were mildly ill. The highest number of patients (34.6%) were moderately ill, while 14.1% and 2.6% were markedly ill and severely ill, respectively. Among the moderately ill patients, more than half (63%) were patients with schizophrenia, 18.5% were patients with delusional disorder, and 18.5% were patients with schizoaffective disorder. Most of the patients (43.6%) presented moderate functioning deficiency, while 38.5% of the patients presented severe deficiency, according to the GAFS score. When assessed with the ABAS, we observed that almost half of the patients (44.9%) showed an average functioning across skill areas in the conceptual, social, and practical domains. A percent of 67.9% of the patients presented an average QoL, while 15.4% and 12.8% showed a very low and low QoL. QoL was not influenced by the patients' symptomatology, gender, and education level. Having children, family support, better social and conceptual skills, and a higher perceived level of recovery was correlated with an increased QoL, hierarchical multiple regression R = 0.379, (9, 68) = 2.616, and = 0.012. : Psychiatric interventions in psychosis should focus not only on symptoms' control, but also on improving social and family support, as well as adaptive skills to increase the patients' QoL.
: 当前的精神科护理越来越关注患者的生活质量（QoL）。研究仍在努力确定影响 QoL 的主要因素。本研究旨在评估患有慢性精神病谱系障碍患者的生活质量及其与症状、功能、适应行为和感知康复水平的关系。: 该研究纳入了 78 例慢性精神病患者。采用阳性和阴性综合征量表（PANSS）和临床总体印象量表严重程度（CGI-S）量表评估症状和疾病严重程度。使用总体功能评估量表（GAFS）和适应行为评估系统 II（ABAS-II）-成人形式评估患者的功能，应用生活质量量表（QOLI）评估生活质量。: 根据 CGI-Severity 量表，20.5%的患者处于边缘性精神疾病状态，24.4%为轻度疾病。大多数患者（34.6%）为中度疾病，14.1%和 2.6%分别为明显疾病和严重疾病。在中度疾病患者中，超过一半（63%）为精神分裂症患者，18.5%为妄想障碍患者，18.5%为分裂情感障碍患者。根据 GAFS 评分，超过一半（43.6%）的患者存在中度功能缺陷，38.5%的患者存在严重功能缺陷。根据 ABAS 评估，我们观察到近一半（44.9%）的患者在概念、社会和实践领域的技能领域表现出平均功能。67.9%的患者表现出平均生活质量，15.4%和 12.8%表现出非常低和低的生活质量。生活质量不受患者的症状、性别和教育程度的影响。有孩子、家庭支持、更好的社会和概念技能以及更高的感知康复水平与更高的生活质量相关，分层多元回归 R = 0.379，（9，68）= 2.616， = 0.012。: 精神病学干预应不仅关注症状的控制，还应关注改善社会和家庭支持以及适应技能，以提高患者的生活质量。
