Japanese Diet and Mortality, Disability, and Dementia: Evidence from the Ohsaki Cohort Study.

The Japanese dietary pattern has long been discussed as one of the factors behind the longevity of Japanese people. However, the health benefits of the Japanese dietary pattern have not been fully elucidated. We published the first report in the world regarding the relation between the Japanese dietary pattern and cardiovascular disease mortality in 2007 using cohort studies including Japanese residents of Ohsaki City, Miyagi Prefecture, Japan. Since then, we have developed the Japanese Diet Index (JDI) that was based on previous findings to assess the degree of the Japanese dietary pattern and to advance the evidence on the health effects of the Japanese dietary pattern. So far, we have explored the associations between the JDI score (in quartiles) and various outcomes. For all-cause mortality, in comparison to Q1 (the lowest), the multivariable hazard ratios (HRs) and 95% confidence intervals (95%CIs) were 0.92 (0.85-1.00) for Q2, 0.91 (0.83-0.99) for Q3, and 0.91 (0.83-0.99) for Q4 (the highest). For functional disability, the multivariable HRs (95%CIs) were 0.94 (0.81-1.09) for Q2, 0.90 (0.77-1.05) for Q3, and 0.79 (0.68-0.92) for Q4. For dementia, the multivariable HRs (95%CIs) were 0.88 (0.74-1.05) for Q2, 0.87 (0.73-1.04) for Q3, 0.79 (0.66-0.95) for Q4. In addition, people with higher adherence to the Japanese dietary pattern also showed decreases in disability and dementia risks. The purpose of this article was to review all six papers, summarize the health effects of the Japanese dietary pattern, and discuss implications for future research.