Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Department of Neurology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Viruses. 2022 Apr 20;14(5):849. doi: 10.3390/v14050849.
Various symptoms have been associated with COVID-19, but little is known about the impacts of COVID-19 on the sensory system, risk factors, and the duration of symptoms. This study assesses olfactory, gustatory, hearing, and vestibular systems after COVID-19.
This cross-sectional, single-center study involved 50 patients one to six months after COVID-19 and reports their patient records and the extent, onset, and duration of olfactory, gustatory, hearing, and balance disorders using questionnaires during and after COVID-19. Sensory symptoms were objectively studied using the following clinical tests after COVID-19 Sniffin' Sticks, taste tests, tone/speech audiometry, and video head impulse test.
Post-COVID-19-patients were suffering from olfactory and gustatory impairment for up to six months. According to the Dizziness Handicap Inventory, balance disorders were less noticed: Overall, about 40% of the patients during COVID-19 and nearly all patients recovered within six months. After COVID-19, clinical tests revealed that 75% were suffering from hyposomnia/anosmia, and 20% of all patients reported mild hypogeusia for up to six months. Vestibular disorders and hearing impairment rarely/did not occur. Females were significantly more affected by sensory impairments than males.
COVID-19 particularly caused olfactory and gustatory impairment; balance disorders were present too; vestibular and auditory symptoms were negligible.
多种症状与 COVID-19 相关,但对于 COVID-19 对感觉系统的影响、风险因素以及症状持续时间知之甚少。本研究评估了 COVID-19 后的嗅觉、味觉、听觉和前庭系统。
本横断面、单中心研究纳入了 COVID-19 后 1 至 6 个月的 50 名患者,报告了他们的病历以及 COVID-19 期间和之后使用问卷评估的嗅觉、味觉、听力和平衡障碍的程度、发病和持续时间。使用以下临床测试在 COVID-19 后客观研究感觉症状:Sniffin' Sticks、味觉测试、音/语音测听和视频头脉冲测试。
COVID-19 后患者的嗅觉和味觉障碍可持续长达 6 个月。根据头晕障碍量表,平衡障碍较少被注意到:总体而言,约 40%的患者在 COVID-19 期间出现平衡障碍,几乎所有患者在 6 个月内恢复。COVID-19 后,临床测试显示 75%的患者患有嗅觉缺失/障碍,20%的患者报告长达 6 个月的轻度味觉减退。前庭障碍和听力障碍很少/未发生。女性比男性更容易受到感觉障碍的影响。
COVID-19 特别引起嗅觉和味觉障碍;平衡障碍也存在;前庭和听觉症状可忽略不计。