Young Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Departments of biotechnology, Uskudar University, Istanbul, Turkey.
Int J Pharm. 2022 Aug 25;624:121878. doi: 10.1016/j.ijpharm.2022.121878. Epub 2022 May 28.
The buildup of nonionic surfactants in the aqueous environment produces niosomes. The usage of niosomes is becoming increasingly frequent due to their sustainability, low cost of components and assembly, large-scale manufacture, and, finally, easy maintenance of the niosomes to the other. Because of their nonionic characteristics, niosomes play a critical role in medication delivery systems. Controlled release and targeted distribution of niosomes to treat cancer, infectious illnesses, and other disorders are one of their most important properties. Niosomes can also be injected by ocular and transdermal routes, which are less common than oral and parenteral administration. Using niosomes to manufacture biotechnology goods and novel vaccines is one of the most exciting research fields today. The molecular structure of niosomes, the physicochemical characteristics of nonionic surfactants in their formulation, the influence of external stimuli on niosomes, the many methods of niosomes administration, and their diverse therapeutic qualities are all explored in this study.
非离子型表面活性剂在水环境中的积累会产生囊泡。由于其可持续性、低组件和组装成本、大规模制造以及对其他物质的囊泡易于维护，囊泡的使用越来越频繁。由于其非离子特性，囊泡在药物传递系统中起着关键作用。囊泡的控制释放和靶向分布可用于治疗癌症、传染病和其他疾病，这是它们最重要的特性之一。囊泡也可以通过眼部和透皮途径注射，这比口服和肠胃外给药更少见。使用囊泡制造生物技术产品和新型疫苗是当今最令人兴奋的研究领域之一。本研究探讨了囊泡的分子结构、配方中非离子型表面活性剂的理化特性、外部刺激对囊泡的影响、囊泡给药的多种方法以及它们的多种治疗特性。
