Lens Marko
Leeds Institute of Medical Research, University of Leeds, Leeds LS9 7TF, UK.
Pharmaceutics. 2025 Feb 21;17(3):287. doi: 10.3390/pharmaceutics17030287.
In an era of significant developments in cosmetic chemistry and growing demand for efficacious skincare products, the efficient delivery of active molecules has been a challenge in formulations of cosmetics. In order to improve the performance of active compounds, the use of different nanotechnology-based systems have been explored in cosmetic chemistry. Niosomes, self-assembled vesicular nanocarriers, have been used in the cosmetic industry since the 1970s. The aim of this review is to provide a comprehensive overview of recent advancements in the encapsulation of active cosmetic compounds using niosomes as potential carriers for their sustained and targeted delivery. The review discusses the physicochemical, pharmacokinetic and pharmacodynamic properties of niosomes, including preparation methods, advantages and limitations. Various applications of niosomes in the cosmetic industry are presented together with the permeation and efficacy data from conducted in vitro and in vivo studies. Future perspectives of these nanocarriers for cosmetic applications are highlighted.
在化妆品化学取得重大进展且对高效护肤品需求不断增长的时代，活性分子的有效递送一直是化妆品配方中的一项挑战。为了提高活性化合物的性能，人们在化妆品化学中探索了使用不同的基于纳米技术的体系。自20世纪70年代以来，非离子表面活性剂囊泡（Niosomes），即自组装囊泡纳米载体，已被应用于化妆品行业。本综述的目的是全面概述使用非离子表面活性剂囊泡作为活性化妆品化合物的潜在载体进行持续和靶向递送的包封方面的最新进展。该综述讨论了非离子表面活性剂囊泡的物理化学、药代动力学和药效学性质，包括制备方法、优点和局限性。介绍了非离子表面活性剂囊泡在化妆品行业的各种应用以及来自体外和体内研究的渗透和功效数据。强调了这些纳米载体在化妆品应用方面的未来前景。
