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原发性肉阜病变的临床和组织病理学特征。

Clinical and histopathological profile of primary caruncular lesions.

机构信息

Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India (A Unit of Medical Research Foundation, Chennai, India), India.

Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

出版信息

Indian J Ophthalmol. 2022 Jun;70(6):1975-1981. doi: 10.4103/ijo.IJO_2724_21.

DOI:10.4103/ijo.IJO_2724_21
PMID:35647965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9359247/
Abstract

PURPOSE

To provide a retrospective analysis of lesions of the caruncle which have been very rarely reported in the literature.

METHODS

A retrospective review of all the caruncular lesions between January 2000 and January 2020 was done at a single tertiary eye care hospital. The lesions were classified as benign and malignant lesions. Clinicopathological correlation was done for the excised lesions.

RESULTS

A total of 87 caruncular lesions were included in the study. Males (59%) were affected more than females (41%). The mean age at presentation was 44 ± 20 years. The mean duration of complaint was 36 ± 62 months. A total of 36 patients underwent surgical excision whereas the rest opted for conservative management. Recurrence was noted in five patients. Fifteen different types of lesions were identified histopathologically. Benign lesions (78%) were far more common than malignant ones (22%). Epithelial inclusion cyst was the most common benign lesion and sebaceous gland carcinoma was the most common malignant lesion. Correct clinicopathological correlation was seen in 52.7% of the cases. Caruncular tuberculosis, oncocytoma, and basosquamous cell carcinoma were some of the rare lesions.

CONCLUSION

Caruncular lesions are uncommon and very diverse, which makes clinical diagnosis challenging. Epithelial inclusion cyst and sebaceous gland carcinoma were the most common benign and malignant lesions respectively. Correct clinicopathological correlation was seen in more than half of the cases.

摘要

目的

对文献中鲜有报道的穹隆部病变进行回顾性分析。

方法

在一家三级眼科医院对 2000 年 1 月至 2020 年 1 月期间所有的穹隆部病变进行回顾性分析。病变分为良性和恶性病变。对切除的病变进行临床病理相关性分析。

结果

研究共纳入 87 例穹隆部病变,男性(59%)多于女性(41%)。就诊时的平均年龄为 44 ± 20 岁。平均发病时间为 36 ± 62 个月。共有 36 例患者接受了手术切除,其余患者则选择了保守治疗。5 例患者出现复发。组织病理学共发现 15 种不同类型的病变。良性病变(78%)远多于恶性病变(22%)。上皮包涵囊肿是最常见的良性病变,而皮脂腺癌是最常见的恶性病变。在 52.7%的病例中,观察到了正确的临床病理相关性。穹隆部结核、嗜酸细胞瘤和基底细胞鳞状细胞癌是一些罕见的病变。

结论

穹隆部病变罕见且种类繁多,这使得临床诊断具有挑战性。上皮包涵囊肿和皮脂腺癌分别是最常见的良性和恶性病变。在超过一半的病例中观察到了正确的临床病理相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/5b5b8798d581/IJO-70-1975-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/206b38712969/IJO-70-1975-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/a3f381679a3d/IJO-70-1975-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/16932010a463/IJO-70-1975-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/5b5b8798d581/IJO-70-1975-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/206b38712969/IJO-70-1975-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/a3f381679a3d/IJO-70-1975-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/16932010a463/IJO-70-1975-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe9/9359247/5b5b8798d581/IJO-70-1975-g004.jpg

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Eye Contact Lens. 2018 Sep;44 Suppl 1:S316-S319. doi: 10.1097/ICL.0000000000000278.
3
Histopathological study of lesions of the caruncle: a 15-year single center review.对肉阜病变的组织病理学研究:一项 15 年的单中心回顾。
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4
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Eye (Lond). 2025 Feb;39(3):424-435. doi: 10.1038/s41433-024-03560-w. Epub 2024 Dec 23.
5
Combining Surgery, Radiotherapy, and Topical Chemotherapy to Prevent Primary Orbital Exenteration for Atypical Caruncular Melanoma: A Case Report.联合手术、放疗和局部化疗预防非典型泪阜黑色素瘤的原发性眼眶内容剜除术:一例报告
Case Rep Ophthalmol. 2024 Mar 15;15(1):212-219. doi: 10.1159/000536590. eCollection 2024 Jan-Dec.
Diagn Pathol. 2009 Aug 31;4:29. doi: 10.1186/1746-1596-4-29.
4
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Eye (Lond). 2009 May;23(5):1004-18. doi: 10.1038/eye.2008.316. Epub 2008 Oct 17.
5
Methicillin-resistant Staphylococcus aureus caruncle abscess.耐甲氧西林金黄色葡萄球菌睑裂斑脓肿
Ophthalmic Plast Reconstr Surg. 2007 Mar-Apr;23(2):160-1. doi: 10.1097/IOP.0b013e3180300700.
6
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7
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J Fr Ophtalmol. 2003 Feb;26(2):204-7.
8
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Indian J Ophthalmol. 2002 Mar;50(1):60-1.
9
Measuring the lacunar sulci as a new indicator of shrinkage of the ocular surface.测量腔隙沟作为眼表萎缩的新指标。
Eur J Ophthalmol. 2001 Jul-Sep;11(3):227-32. doi: 10.1177/112067210101100303.
10
Ocular spherulocystosis.眼部球孢菌病。
J Clin Pathol. 1996 Oct;49(10):857-8. doi: 10.1136/jcp.49.10.857.