Centre for Epidemiology and Evidence-Based Practice, Department of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Department of Epidemiology and Health Statistics, The School of Public Health, Fujian Medical University, Fuzhou, Fujian, China.
Hum Vaccin Immunother. 2022 Nov 30;18(5):2078634. doi: 10.1080/21645515.2022.2078634. Epub 2022 Jun 1.
This study aims to provide evidence of hesitancy in receiving the COVID-19 booster vaccine and associated factors in the vaccinated population that have completed a primary vaccination series. An anonymous web-based survey was disseminated to Malaysian adults aged ≥18 years via social media platforms. A total of 1010 responses were collected, of which 43.0% (95%CI 39.9-46.0) declared a definite willingness to receive a COVID-19 vaccine booster, 38.2% (95%CI 35.2-44.3) reported being and only 5.7% (95%CI 4.5-7.4) reported being . Demographically younger participants, those of higher income, Chinese ethnicity and those from the central region reported significantly higher odds of a definite willingness to receive the COVID-19 vaccine booster compared to the reference group (///). Having no side effects with past COVID-19 vaccination was associated with a significantly higher odds of definite willingness (OR = 2.82, 95% CI 1.33-5.99). A lower (range 6-22) pandemic fatigue score (OR = 2.34, 95% CI 1.75-3.22) and higher (range 24-30) preventive practices score (OR = 2.45, 95% CI 1.80-3.34) were also associated with higher odds of definite willingness. Regarding attitudes toward COVID-19 booster vaccine, having fewer concerns about the side effects of booster vaccination and the uncertain long-term safety of multiple COVID-19 vaccinations were found to create greater odds of a definite willingness to receive the COVID-19 vaccine booster. Findings from this study provided insights into demographic characteristics and important behavioral and attitudinal factors associated with COVID-19 vaccine booster hesitancy.
这项研究旨在为已完成初级疫苗接种系列的接种人群中对 COVID-19 加强疫苗接种的犹豫情况及其相关因素提供证据。通过社交媒体平台向马来西亚≥18 岁的成年人发布了匿名在线调查。共收集了 1010 份回复，其中 43.0%（95%CI 39.9-46.0）明确表示愿意接种 COVID-19 疫苗加强针，38.2%（95%CI 35.2-44.3）表示会考虑接种，只有 5.7%（95%CI 4.5-7.4）表示不会接种。与参考组相比，年龄较小、收入较高、华族和来自中心地区的参与者报告明确愿意接种 COVID-19 疫苗加强针的几率显著更高（///）。与过去 COVID-19 疫苗接种无副作用相关的人，更有可能明确表示愿意接种（OR=2.82，95%CI 1.33-5.99）。较低（范围 6-22）的大流行疲劳评分（OR=2.34，95%CI 1.75-3.22）和较高（范围 24-30）的预防措施评分（OR=2.45，95%CI 1.80-3.34）也与较高的明确意愿几率相关。关于对 COVID-19 加强疫苗的态度，发现对加强疫苗接种副作用和多次 COVID-19 疫苗接种长期安全性的担忧较少，更有可能明确表示愿意接种 COVID-19 疫苗加强针。这项研究的结果提供了对与 COVID-19 疫苗加强针犹豫相关的人口统计学特征和重要行为及态度因素的见解。
